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According to the British newspaper "Courrier quotidien", the problem of AIDS lies in the ability of the virus to hide, and thus undetected, then uncontrolled, which means that the patient can never be cured.
But researchers at the University of Illinois at Chicago have made HIV concealed in visible cells for the immune system, claiming that they were about to find a cure.
The researchers say that targeting the TAT gene inside the brain can drive the virus out of hiding, making it vulnerable to the immune system and drugs. Currently used to cope with the disease, Which could pave the way for his control.
The drugs currently used to treat the disease are not the cause of the problem, which the new study attempted to address by focusing efforts on the gene, according to the National Academy of Sciences PNAS recently.
The injured are currently being treated with "antiretroviral drugs", which slow the progression of the disease by reducing the replication of the virus in the blood of the carrier, known as "Viral Pregnancy".
According to the researchers, the gene activation TAT Will lead to "Properly cause the production of infected cells, then distinguish them and destroy them by the immune system".
Professor of Biological Engineering, senior researcher in the study, Ji Liang said: "During the course of infection, HIV DNA enters the cell nucleus of the human body that houses it and integrates into your own genome, TAT When seizing the cellular mechanism to produce new copies of the virus, they finally explode in the cell to infect neighboring cells by infection.
He added: "The infected cells function normally despite the virus, as long as a gene is not activated TAT To produce new copies, and the problem that the mechanism of action of this gene is random, can be active or inactive, and the transformation can occur automatically from inactive to active, and so it will difficult to help the immune system drugs to resist infected cells at the time of their appearance. ".
He continued: "The result of the research is that the targeting of the launch platform of the virus is Jane TAT With drugs that activate it, cells will be sufficiently infected and destroyed by the immune system. "
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According to the Daily Mail newspaper, the problem of AIDS is the ability of the virus to hide and, therefore, not to be detected and then uncontrolled, which means that the patient can never be cured.
But researchers at the University of Illinois at Chicago have made HIV concealed in visible cells for the immune system, claiming that they were about to find a cure.
The researchers say that targeting the TAT gene inside the brain can drive the virus out of hiding, making it vulnerable to the immune system and drugs. Currently used to cope with the disease, Which could pave the way for his control.
The drugs currently used to treat the disease are not the cause of the problem, which the new study attempted to address by focusing efforts on the gene, according to the National Academy of Sciences PNAS recently.
Victims are currently being treated with "antiretroviral drugs" that slow the progression of the disease by reducing the virus's doubling in blood, called "viral pregnancy"..
According to the researchers, the gene activation TAT Will "cause the production of infected cells sufficiently, and then be identified and destroyed by the immune system."
"During the course of infection, HIV DNA enters the nucleus of the human body cell that hosts it and integrates it into its own genome to help the gene," he said. said Ji Liang, a professor of biomedical engineering. TAT When entering the cellular mechanism to produce new copies of the virus, they eventually explode in the cell to infect neighboring cells.
"Infected cells function normally despite the virus, as long as the gene is not activated TAT Produce new copies and the problem of the mechanism of action of this gene is random, can be active or inactive, and can be the automatic switch from inactive to active. It will therefore be difficult to help the immune system drugs to resist infected cells at the time of their appearance. ".
He continued, "The research found that, targeting the launch platform of the virus, Jane TAT With the drugs that activate it, the infected cells will be properly produced and destroyed by the immune system. "
