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The Chinese scientist He Jiankui, whom no one knew until yesterday, excited the scientific and medical world by claiming that he had modified genes on embryos in seven different couples during an insemination. artificial, thus creating HIV-resistant twins. Scientists around the world have condemned his experience on "designing a baby," stating that it was about opening Pandora's box.
He was also working as an Assistant Professor at the China University of Science and Technology of Shenzhen in Shenzhen and claims to have used CRISPR gene-switching technology on embryos from seven different couples during the artificial insemination process, which resulted in the birth of twins this month.
Gemini were born in good health a few weeks ago, and they call Lulu and Nana. If he's right, these are the world's first babies born with a modified gene. He says that he has changed the embryonic gene of twins in the hope that babies become resistant to HIV.
His allegations are not confirmed by independent sources and he keeps secret the details of the identity of the twins. He nonetheless disclosed this information to the AP news agency in view of a conference in Hong Kong, where he published the results of his work. On "Jutjub", he hung up a video with his story.
– I feel like a strong responsibility that it is not just to be the first, but to be an example. The company will decide what will happen next, he said.
Climbing IMMUNE ON HIV
"Newspaper" reports that Chinese scientists have published this month on the Internet medical documents revealing the details of this research, including the recruitment of couples on a voluntary basis. He says that the result of all these efforts is the birth of twins immunized against HIV, thanks to the CRISPR technology. He says his father was HIV-positive and his mother was not.
"The goal was to change the baby's genes to protect him from future HIV infections," he told AP.
Although this is potentially an incredible medical achievement, the scientific community is very concerned about the ethics of the process. As soon as he presented his work to the public, he immediately became the target of much controversy and repeated debate about "Designed Baby". The university has distanced itself from Hea, stating that he had been suspended and that he had not received his salary since February, and that an investigation was underway. He should not return to work until January 2021, the university said in a statement, adding that he would immediately hire experts to investigate the case.
AND AMERICAN SCIENTIFIC UNDER ISTRAGH
At the same time, another scientist is currently under investigation for suspecting his involvement in changing the genes of Chinese twins, according to ABC News. Rice University has launched an investigation into a professor of biochemical and genetic engineering, Dr. Michael Dim.
They said from the university that they were unaware of his work and that this process had not been carried out according to their knowledge in America, where genetic modifications occurred. human embryos are illegal. Smoke said that he was in China when the participants agreed to make a genetic modification. He pointed out that they had all understood the risks.
"The comparison of gene change with vaccines may be the way the legislator can describe it," he said.
THE PANDORA BOX IS OPEN
The details of the research have not yet been confirmed or published in a scientific journal, a standard protocol, and more than 100 scientists, mostly from China, have condemned the publication of He as a "madness" and behavior contrary to the ethic. Scientists in an open letter claim that the use of CRISPR-Cas9 technology to alter the human embryo gene is very risky, unjustified and undermines the reputation and development of the biomedical community in China.
– Leading experiments on humans can only be described as crazy. Pandora's box is open. We still have hope of closing it before it's too late – says about 120 scientists in a letter published on Chinese websites.
Yang Zhengang, a professor at Fudan University, told Reuters that he had signed the letter because changing genes is "very dangerous".
China's National Health Commission said it was "very worried" and ordered regional officials to immediately check and clarify the situation.
CRISPR is a molecular tool that allows scientists to modify DNA components. Many scientists are interested in the elimination or treatment of genetic diseases. While CRISPR-cas9 technology is used on adults, genetic modification of embryos is another because all modifications can be passed on to their offspring.
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