NEW YORK: A ketogenic diet, low in carbohydrates and high in fat, could improve the effectiveness of a new class of cancer drugs, have discovered scientists, including an original Indian.
A study, published in the journal Nature, found a strategy to stimulate the tumor-killing potential of targeted therapies on the insulin-activated enzyme, phosphatidylinositol-3 kinase (PI3K) – a family of enzymes involved in cellular functions such as cell growth, proliferation and differentiation.
"Any drug that targets PI3K may not be effective unless patients can maintain low blood sugar levels through a diet or medication." We have shown that if we maintain insulin with the ketogenic diet, it significantly improves the effectiveness of these drugs. said Lewis C Cantley of Weill Cornell Medicine in the United States.
Some of the most common genetic mutations observed in cancerous tumors affect PI3K.
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Anti-carcinogenic herbs and spices
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Although one can never be sure of what can trigger the onset of this deadly disease, it is important to take the necessary precautions to stay safe. Some foods have anti-carcinogenic properties and can help prevent cancer.
These herbs and spices in your kitchen cabinet can boost your immune system to keep the deadly disease at bay.
Dr. Manoj Kutteri, director of the Atmantan Wellness Center, shares a list of ingredients that can help you fight the disease.
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Turmeric
Feb 3, 2018
A number of studies have shown that curcumin (yellow chemical compound in turmeric) has anti-cancer properties. It has the ability to kill cancer cells and prevent further growth. Curcumin inhibits the growth of various cancer cells in the bones, breast, brain, colon, stomach, bladder, kidneys, prostate and ovaries. It can also kill cancer cells by apoptosis (a programmed cell death).
Ginger
3 Feb, 2018
Ginger was considered ten thousand times more powerful than chemotherapy for the treatment of cancer. It's an antioxidant and a natural cancer fighter. The active compounds 6-gingerol and 6-shogaol have anti-cancer properties against the gastrointestinal tract and contribute to the death of cancer cells.
Garlic
3 Feb, 2018
Garlic is another important spice treating cancer. It has the ability to inhibit the production of carcinogenic properties, accelerate the process of DNA repair and slow the proliferation of cancer cells
Black Pepper
3 Feb, 2018
Black pepper contains antioxidant piperine. A study conducted at the Michigan Cancer Institute concluded that black pepper and turmeric can prevent the growth of cancer stem cells in breast tumors. [196] To highlight the effectiveness of existing therapies, scientists treat mice with drugs used to treat diabetes. and a ketogenic diet.
Although diabetes medications did not have much effect on mice, the ketogenic diet, used clinically for about four decades to control insulin levels, did the best work to prevent spikes in glucose and insulin. tumor growth signals.
"The ketogenic diet proved to be the perfect approach.It reduced glycogen stores, so that mice could not release glucose in response to PI3K inhibition" said Benjamin D Hopkins of Weill Cornell Medicine.
"This suggests that if you can block the glucose spikes and the subsequent return of insulin, you can make the drugs much more effective at controlling the growth of cancer," he said.
However, the researchers warned that the ketogenic diet alone may not necessarily help control cancer growth and in some cases may even be harmful, as in the case of some leukemias.
"We have to make sure that there is no unexpected toxicity," Cantley said.
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Tags cancer diet Drug effectiveness improve Keto