A drug made from capsaicin in hot peppers proven effective against obesity



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Chillies have long been considered to have beneficial effects on health, and now scientists have fought against obesity.

Scientists from the University of Wyoming's pharmacy school developed a new drug against obesity called Metabocin. an active component in peppers called capsaicin. The team will present its findings at the annual meeting of the Society for the Study of Ingestive Behavior on July 20 in Bonita Springs, Florida.

Capsaicin, which makes spicy peppers spicy, has beneficial effects on health. However, scientists have struggled with how to use the compound without irritating the stomach or making it difficult to swallow, because of how fiery it is.

"To reduce this effect, we have prepared a polymer-coated formulation for capsaicin, which will release capsaicin much more slowly," said Baskaran Thyagarajan, associate professor of pharmacy and neuroscience at the University. of Wyoming and leader of the study, Newsweek . "The person taking it will not feel the burning pain, but will enjoy the effect of capsaicin for longer." [19659002] According to the study, Metabocin, an oral drug, prevents white fat cells from storing energy and burning energy.This turns white fat into brown fat, which is more metabolically active and helps you burn In the Thyagarajan study, metabocine containing capsaicin was administered to mice, Thyagarajan said researchers expected mice to eat less food than mice that did not take the drug. However, what they saw was very different.

"Both groups ate equal amounts of food and received equal amounts of energy, but the capsaicin-fed group lost weight," Thyagarajan said. "We were totally surprised."

 GettyImages- 169646059 A seller sells hot peppers in the Philippines. Capsaicin, which makes spicy peppers, has been shown to be beneficial for health. NOEL CELIS / AFP / GETTY IMAGES

Scientists have studied mice for eight months and found no toxicity at home as a result of the drug. They plan to test the drug for longer periods of time, but the absence of negative effects was very encouraging. Not only that, but they found that the drug could do more than just treat obesity.

"Capsaicin not only prevented obesity or promoted weight loss, it was also very effective at increasing insulin sensitivity in mice," said Thyagarajan. This finding could help people with diabetes who have problems with insulin sensitivity.

Despite these findings, this does not mean that eating chillies will help somebody lose weight. Thyagarajan has calculated the exact amount of capsaicin needed to help humans lose weight – a quantity that someone can not get just by eating a chilli. He explained, "Consuming chillies will definitely have benefits, but you will not be able to get all the benefits of capsaicin."

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