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A researcher from an Australian university discovered that cinnamaldehyde, a component of cinnamon essential oil, can help fight superbugs by inhibiting the development of the most potent antibiotic-resistant bacteria [19659002] Halim Topa, a doctor from the Swinburne University of Technology, discovered that cinnamaldehyde, which is responsible for the unique taste of cinnamon, can be used to develop antibiotic alternatives, to treat chronic superbugs to biofilm
of cinnamon essential oil, it is not widely used in the pharmaceutical industry, said Topa
"We sought to look for molecular activity of this oil, focusing on its major component, cinnamaldehyde. It is the compound that gives its flavor to cinnamon. "
There is an urgent need to develop alternatives to antibiotics to treat chronic biofilm-induced infections, as can happen with urinary catheters and artificial joints." Bacteria, Topa sought to alter the behavior of bacteria in disrupting bacterial communication to prevent biofilm formation
"We hypothesized that the use of natural antimicrobials, such as essential oils, could interfere with biofilm formation. Thus, we focused on the impact of different concentrations of cinnamaldehyde in different stages of biofilm development, "she notes.
In the study published in the journal Microbiology, Topa tested the effect of different concentrations of cinnamaldehyde on biofilms Pseudomonas aeruginosa strain of bacteria
The results showed a sublethal concentration of cinnamaldehyde controlled the Pseudomonas aeruginosa dispersion and biofilm development.
"Humans have a long history of using natural products to treat infections, and there is a renewed interest in such antimicrobial compounds.Natural products can offer a promising solution to this problem," he said. Topa.
She is currently studying the incorporation of cinnamaldehyde into nanofibers in dressings
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