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WASHINGTON (XINHUA) – A team of researchers from the United States has identified a gene in mice that can reverse wrinkles and hair loss and could be applied to humans at the same time. future, local media reported
. loss are the characteristics of aging, and if they could be reversed? Genetics researchers from the University of Alabama in Birmingham (UAB) asked, saying that they made a breakthrough.
In the study, the mice received an antibiotic that caused changes in their gene.
The antibiotic induces a mutation and mice developed wrinkled skin and suffered significant hair loss in a few weeks.
The mutation was caused by mitochondria, small organelles in the cell that function as the digestive system of the cell, becoming dysfunctional.
Mitochondrial function was reestablished, mice returned to smooth skin and thick fur, indistinguishable from a healthy mouse of the same age.
"To our knowledge, this observation is unprecedented," said Keshav Singh, professor of genetics at UAB. School of Medicine
Singh said that the mouse model should provide an opportunity for the development of preventive and therapeutic drug development strategies to increase mitochondrial functions for treatments. t diseases associated with aging and other diseases.
In humans, there is a decline in mitochondrial function during aging, and mitochondrial dysfunction may result in age-related diseases. Depletion of DNA in mitochondria is also associated with human mitochondrial diseases, cardiovascular disease, diabetes, neurological disorders associated with age and cancer
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