Hypertension in pregnancy can affect cardiovascular health for life



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  1. Women who suffer from hypertensive disorders during pregnancy are at high risk for hypertension, diabetes, and hypercholesterolemia later in life

Abstract: http: // annals. org / article / doi / 10. 7326 / M17-2740

Editorial: http: // annales. org / aim / article /doi/10.7326/M18-1443

The URLs are brought online when l & # 39; embargo is lifted

Women with a history of pre-eclampsia or gestational hypertension during pregnancy developed chronic hypertension two to three times higher and had higher than 70% higher rates of type 2 diabetes and hypercholesterolemia, respectively. and 30% to women's normal blood pressure during pregnancy. These results suggest that women with complicated pregnancies with hypertension can benefit from cardiovascular screening throughout their lives. The study is published in Annals of Internal Medicine

Between 10 and 15% of women suffer from hypertensive complications during pregnancy, such as preeclampsia or gestational hypertension, and substantial evidence shows that these women are more likely to have a heart attack or stroke. later in life, even if their blood pressure returns to normal immediately after pregnancy. What is less clear is how far they are also more likely to develop risk factors for cardiovascular disease and when these risk factors begin to appear after pregnancy.

Researchers at Brigham and Women's Hospital and Harvard TH Chan School of Public Health studied more than 58,000 women enrolled in Study II on the health of nurses (NHS II) who n & # 39; 39 had no cardiovascular disease or risk factors at the time of registration and had given birth at least once. Women were followed for a diagnosis of chronic hypertension and high cholesterol confirmed by a physician and confirmed type 2 diabetes from their first birth until 2013 with a mean follow-up of 25 to 32 years . Compared with women who had normal blood pressure during pregnancy, those with preeclampsia or gestational hypertension were significantly more likely to develop cardiovascular risk factors throughout the follow-up and also developed these risk factors earlier and sooner. after pregnancy

. researchers, these findings suggest that preeclampsia and gestational hypertension can alert women and their health care providers about their future cardiovascular health. In addition to screening, women who have had these common complications should talk to their doctor and adopt a heart-healthy diet and lifestyle, as they would if they had a family history of cardiovascular disease.

Media Contact: For an embargoed PDF, please contact Lauren Evans at [email protected]. To interview the senior author, Jennifer Stuart, ScD, please contact Elaine St. Peter at the address [email protected].

  1. Regular use of marijuana is associated with the development of respiratory problems

Abstract: http: // annals. org / purpose / article / doi / 10. 7326 / M18-0522 ]

The URLs are put online when the embargo is lifted

Evidence of low intensity suggests that regular use of marijuana (at least once a week for one year) is associated with coughing, sputum production, and wheezing. Researchers have not found enough evidence to determine the effect of marijuana use on lung function. The results of a systematic review and a meta-analysis are published in Annals of Internal Medicine.

Marijuana use is increasing in the United States, with about 13 percent of adults and 21 percent of young adults using regular marijuana. Its widespread use and growing social acceptance mean that a better understanding of its effects on health is needed. Since smoking remains the main method of consumption, the similarities between marijuana and tobacco smoke are of public health concern.

National Institutes of Health researchers examined data from 22 published studies to determine the association between marijuana use and respiratory symptoms, pulmonary function and obstructive pulmonary disease in adolescents and adults. Two prospective studies have shown that the use of marijuana was associated with an increased risk of respiratory problems. Data on lung function and obstructive pulmonary disease were inadequate. The authors propose long-term longitudinal studies examining the long-term pulmonary effects of the daily use of marijuana

. Media Contact: For an embargoed PDF, please contact Lauren Evans at [email protected]. To interview the senior author, Mehrnaz Ghasemiesfe, MD, please contact her directly at [email protected].

  1. Genomic Testing Can Identify Less Common Diagnoses Affecting Patient Care

Abstract: http: // annals. org / objective / article / doi / 10. 7326 / L18-0177 ]

The URLs are put online when the embargo is lifted

Genomic tests are used to identify alternative and less frequent diagnoses that have important consequences for treatment and management. The researchers used the example of a 69-year-old woman who had been diagnosed with autosomal dominant polycystic kidney disease (ADPKD) to illustrate this point. Their case report is published in Annals of Internal Medicine.

Patients with bilateral renal cysts, hypertension, and chronic renal failure are typically diagnosed with ADPKD. The doctors treated a woman with a family history of PKRAD from a paternal aunt and a cousin, but not his father. After receiving a kidney from one of his adult daughters, the patient continued to develop benign renal cysts in the given kidney. A genomic test revealed the mutation responsible for Birt-Hogg-Dube syndrome, a rare genetic disease that increases the risk of certain types of tumors. This information has helped doctors determine an appropriate treatment strategy for managing their condition. According to the authors, this case shows how the genomic test can be used to find rare diagnoses that may affect treatment decisions.

Media Contact: For an embargoed PDF, please contact Lauren Evans at [email protected]. To interview the lead author, Meyeon Park, MD, please contact her directly at [email protected].

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Jade R. Blue, BA (Hons)

Annals Graphic Medicine

Abstract: http: // annales. org / objective / article / doi / 10. 7326 / G17-0019

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