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The researchers used fruit flies as a model of alcoholism in a living organism.
American neurologists have been able to establish why there was an alcohol addiction and what makes "bound" to break up and start drinking again after a long period of abstinence. On the conclusions of the experts on this account, according to a press release MedicalXpress.
In insects, initially trained to use alcohol, scientists have deactivated genes that are thought to be involved in the formation of alcohol dependence. Thus, experts have discovered a special ability of the Notch gene.
According to the authors of the study, this gene is involved in the action of the signaling network, which also involves a D-2 type receptor that recognizes the dopamine neurotransmitter, responsible for the feeling of satisfaction and pleasure. As noted by biologists, this receiver not only gives the animal a pleasant sensation, it is also responsible for the memory of the experience. Scientists believe that he is responsible for the formation of addiction.
They found that after the adoption of alcohol and the impact on alcoholului, Notch in the common signaling system replaces the replacement of an amino acid and includes in particular the D-2 type receiver. In other words, the consumption of alcohol in the body immediately evokes the memory of sensations associated with the consumption of alcohol.
Scientists said: in order to activate the memory of the man does not have a glass of wine. If you then stop drinking, the memory wakeup mechanism disappears – this discoloration will take about an hour.
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