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The assignment of human lines occurred about 618,000 years ago.
A team of New York Medical College virologists, Einstein Robert Burke, conducted a study that revealed that the human papillomavirus had infected Homo sapiens after close contact with Neanderthals.
There are more than 600 strains of HPV, but the two most dangerous forms – HPV16 and HPV18 – have been transmitted by Neanderthals, scientists say.
Remember that HPV is a sexually transmitted virus. The most common types and the most dangerous to health are HPV16 and HPV18 types, as well as some strains, which are rare in humans.
Strains 16 and 18 are dangerous for humans because they can cause the formation of cervical cancer, anus in men and women, penis and squamous cell carcinoma of the larynx . Most often, this virus is sexually transmitted, but they can also infect the baby during delivery if the mother is carrying the virus. As for the treatment, it is individually selected for the patient. This may be antibiotics, cryotherapy or laser removal of formations that have appeared as a result of HPV. Often, during treatment, we connect immunologists – said "Reedus", the doctor-dermatologist of the Lazer Maxima Clinic Yelena Pak.
The authors of the new study explained that they were studying the genetics of HPV16 and HPV18 for many years, these strains playing the role of powerful oncogenic factors.
To discover the origin and evolutionary history of these papillomaviruses, scientists have isolated HPV16 particles infected with rhesus macaque and miniature monkeys as well as miniature monkeys representing Old and New monkey monkeys.
They then compared their genomes and discovered that primate-infected viruses are very similar genetically. This suggests that the specialization of papillomavirus in the infection of various tissues has begun even before their transition to humans. The process of adaptation to the body has taken nearly 40 million years.
During the study, the researchers also compared human 212 HPV16 genotypes isolated from patients around the world. These data helped scientists reconstruct the history of the disease.
Was it about the separation of the human lineage about 618,000 years ago, after which HPV16 was divided into four subtypes spread throughout all of Eurasia? Just then, Neanderthals spread to the continent.
Scientists have explained that the subtype A of HPV16 in Africa is still virtually non-existent, but that in Europe A1-3 and Asia-A4 varieties are widespread.
Our study suggests that in people from Africa, the virus is inherited from Neanderthals, crossbreeds and generally sexual intercourse over the past 80,000 years. With less confidence, the same conclusions can be drawn about other HPV16 papillomavirus embodiments – concluded the researchers.
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