[ad_1]
New York, November 11 (IANS): Salmonella, a common bacterium that causes food-borne illnesses, is resistant to several antibiotics used to treat infections, suggests new research. For this study, researchers sequenced and studied the genomes of 90 strains of a specific serological variant (serovar) of Salmonella enterica, called S. Typhimurium.
When the action of antibiotics in each of the 90 strains was tested, it was discovered that the vast majority of them were resistant to different classes of antibiotics being part of the arsenal of drugs. The study, published in the journal PLOS ONE, also identified 39 genes responsible for antibiotic resistance. "It is striking to see that S. Typhimurium is resistant to the antibiotics that can be used to treat the disease.These drugs are available to doctors to fight against infections that are resistant," said Amanda Aparecida Seribelli of the United States. University of Sao Paulo in Brazil. Salmonella comprises two species, S. bongori and S. enterica.
The latter is the type species, with a large number of subspecies and serovars that cause more food-borne infections than any other species in Brazil and in the world. The human and animal intestinal tract is the main natural reservoir of this pathogen, with poultry, pork and related food products being the main vector of transmission. The six subspecies of S. enterica are subdivided into 2,600 serotypes. The most important subspecies of S. enterica from the epidemiological point of view is the subspecies S. enterica enterica, responsible for the foodborne infection called salmonellosis.
The symptoms are diarrhea, fever, stomach cramps and vomiting. The most frequently isolated serotypes of this subspecies are S. Typhimurium and S. Enteritidis. All 90 strains analyzed in the study belonged to S. Typhimurium. Research has focused on sequencing the entire genome of the major bacteria responsible for acute diarrohea. According to the study, 65 strains were resistant to sulfonamides, 44 to streptomycin, 27 to tetracycline, 21 to gentamicin and seven to ceftriaxone, a cephalosporin antibiotic.
[ad_2]
Source link
