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FluQuadri will be India's first quadrivalent vaccine that will provide broader protection against the four strains of influenza virus.
Sanofi Pasteur, the vaccines division of Sanofi, recently announced the launch of its FluQuadri® 4-strain influenza vaccine in India. FluQuadri® will be India's first quadrivalent vaccine to provide broader protection against influenza to the population over 3 years old.
Currently, the majority of seasonal influenza vaccines are trivalent, which means they protect against: two A strains and one influenza B (B / Victoria or B / Yamagata) line. However, in recent influenza seasons, co-circulation of both B lineages has been consistently observed, making it difficult for the World Health Organization (WHO) to recommend which strain B should be incorporated into vaccines. trivalent antigens. Given the evolution of epidemiology, quadrivalent vaccination represents the next logical step towards an advanced level of protection. WHO includes quadrivalent influenza vaccines in its recommendations, stating that "quadrivalent influenza vaccines that may provide broader protection against influenza B viruses become available and that recommendations should not be limited to trivalent vaccine" [19659004]. Vijay Yewale, director and pediatrician consultant, Dr.Ewale Multispecialty Hospital, Navi Mumbai; and Chief, ICH, Apollo Hospitals, Navi Mumbai said, "There are two different subtypes of influenza type B causing diseases in humans. The vaccine available up to now only includes one subtype of influenza B and thus protects against only that included in the vaccine. The influenza vaccine is freshly prepared twice a year and the types of influenza viruses, A and B, are included in the vaccine based on scientific predictions made about types likely to circulate throughout the year. During the 2000-2010 decade, 50% of cases in Europe and the US, the disease causing subtype B circulating was different from that included in the vaccine. This would leave vaccinated individuals unprotected against the subtype that is not included in the vaccine. A quadrivalent vaccine provides protection against the four subtypes – two subtypes Influenza B and Influenza A. This protects them against all circulating subtypes. "
India has also seen influenza B strains circulating. The 2017 annual report of the Integrated Disease Surveillance Program (IPD) indicated that following the high number of influenza cases and cases of Influenza in Gujarat, a committee of experts noted that one of the main reasons for influenza outbreak in Gujrat was and B subtypes of influenza virus circulating, but not H1N1, leading As a result, the committee suggested that in the future, in all IEC (Information Education Communication) documents, the words "swine flu" should be replaced by the words "influenza". and in another case, an acute febrile illness surveillance project, anchored at the Karnataka Manipal Center for Virus Research, found that influenza accounted for almost 20% of fevers in rural areas of 10 states in and during the years when the H1N1 flu is low. In these areas, the circulation of H3N2 and Influenza B tends to spread.
"Sanofi Pasteur remains at the forefront of innovation to fight the burden of underestimated influenza.Our expertise of more than 60 years in influenza prevention inspires us to look for Better vaccine solutions to fight the burden of the disease.We are proud to bring this innovation to India, which has experienced quite a lot of influenza outbreaks over the last decade.By putting FluQuadri® on At the disposal of the Indian population, we aim to provide broader protection to people aged 3 and over against this serious illness and its life-threatening complications, "said Jean-Pierre Baylet, Country Head – Sanofi Pasteur South Asia.
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