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London, Oct 26 (IANS) Undergoing bariatric surgery to fight obesity can prevent women from developing womb cancer known as uterine or endometrial cancer, claims a study.
The findings, led by scientists from the University of Manchester, have shown that they have been treated by surgery for obesity and that they have lost weight in their womb.
"For super obese women, it can also reduce cancer risk," said Emma Crosbie, clinical senior lecturer from Manchester.
"Losing weight through dieting is also likely to be effective, but we know that dieting is very hard to do and is often re-gained," she said.
In the study, published in the International Journal of Cancer, the team reviewed nearly 100 women with an average of over 50 – considered to be super obese – had biopsies taken from their wombs during gastric or bypass surgery.
Obese post-menopausal women produce estrogen from their fat stores. But they do not have the ovulation, the lack of progesterone allows the cells in the womb to grow, which increases the risk of cancer.
Inflammatory responses and insulin production are also changed in obese women and can cause cells in the womb to grow.
"Because the reversal of precancerous changes in the womb was so quick, we thought the metabolic consequences of weight loss surgery was crucial," said Crosbie.
However, the researchers stressed that the surgical option was not for everyone, because it was no easy choice.
"It is changing your relationship with food forever," he said. "It's important to remember that surgery can be a dangerous procedure," said Crosbie.
"But for those who choose it, gastric sleeve or bypass surgery can be seen as a preventative measure for womb cancer."
–IANS
rt / soni /
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