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Success in the search for an HIV vaccine, agent responsible for the disease Immunodeficiency Aids: In humans, an active ingredient in the course of a study caused an immune response in monkeys even protected against infection.
Scientists from the American University of Harvard now report in the journal "The Lancet".
In a laboratory study, 72 monkeys were injected with the active substance (Ad26 / Ad26 stronger gp140) and an HIV-like virus. Two-thirds of the animals were thus completely protected against infection by the vaccine.
The research team also undertook a study of 393 healthy adults aged 18 to 50 years from East Africa, South Africa, Thailand and the United States. -United. Part of the group received the active substance, the remaining participants received only one placebo. Medical Professor Dan Barouch of Harvard University said the drug tested had "triggered strong immune responses in humans." It also caused side effects in a few participants – five of them complained of abdominal pain and diarrhea, dizziness or back pain.
"The results are promising, but we must be careful." The data do not prove that people could be protected from HIV by the vaccine.
In the next phase, the drug will be injected at 2,600 women to see if it can actually prevent AIDS. The results are expected in 2021/2022.
Finding an AIDS vaccine is extremely difficult because the avian influenza virus is highly adaptive. Globally, according to the World Health Organization (WHO), about 37 million people are infected with HIV or already living with AIDS. Each year, about 1.8 million people newly infected with the virus, which destroys the body's immune system. About one million people die each year from consequences
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