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A large group of scientists (from the Chan School of Public Health, the US National Cancer Institute and more than 20 other companies and medical centers) discovered a new study according to which increased levels of vitamin D are closely associated with the risk of colorectal cancer. .
This study supports previous evidence that has been considered inconclusive about the relationship of vitamin D to this type of cancer.
Optimal vitamin D concentrations for colon and rectal cancer may be higher than those recommended by the National Academy of Medicine, which is based solely on bone health.
(This study appeared online in the Journal of the National Cancer Institute).
It is believed that vitamin D, known to be effective in maintaining bone health, reduces the risk of colorectal cancer by many pathways related to cellular regulation and growth.
Previous studies have shown unequal results as to whether high concentrations of 25-hydroxyvitamin D-rolling lead to a reduction in the incidence of colorectal cancer or not.
Few randomized clinical trials on vitamin supplements and rectal colorectal cancer showed no effect, but study size, duration of supplements, and response may have contributed to his false results. "To address inconsistencies in previous vitamin D studies and to verify vitamin-related data binding, we analyzed data collected from 17 groups prior to the diagnosis of colorectal cancer," said Stephanie Smith, an epidemiologist at the University of Toronto. 39, Harvard University. Expected, and the use of standards in all studies ".
The study involved the analysis of more than 5,700 cases of rectal colon cancer and 7,100 cases as a control group in the United States, Asia, and Europe.
Only one laboratory test has been widely accepted for new measurements of vitamin D. "In the past, fundamental differences in vitamin D parameters have made it difficult to integrate vitamin D data from from different studies, "said Regina Regler, Ph.D., epidemiologist at the National Institute of Oncology. The calibration of systemic risk detection is systematically around vitamin D levels.
The study showed that vitamin concentrations sufficient for bone health were associated with a rate of 80%. infection was 30% higher and the highest concentrations were associated with a risk of infection of less than 22%. The level of association between higher vitamin levels and a lower risk of infection in women was higher than that of men!
Colorectal cancer is the third most common type of cancer and the third leading cause of death in men and women in the United States with approximately 140,250 new cases and 50,630 deaths expected in 2018.
Dr. Margie Macaulog, Epidemiology at the American Cancer Society and one of the participants in the study: "Currently, the health agency does not recommend vitamin D for prevention colorectal cancers. "
"This study has provided new information that agencies can use when examining evidence to guide vitamin D, and suggests that recommended bone health concentrations may be less than ideal for preventing this type of cancer, "he said.
Vitamin D can be obtained in the diet, supplements and exposure to sunlight, but experts recommend vitamin D as part of a diet because too much of UV exposure is one of the causes of cancer. So, skin, you should be careful.
- Translation: Mohammad Ghazi.
- Verification: Visions of Drakhbani.
- Editing: Suha Yazji.
- Source
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