Scientists discover how "good" fat is related to the feeling of fullness – Xinhua

WASHINGTON, Nov. 15 (Xinhua) – A study published Thursday in the journal Cell revealed how "brown fat" is a type of body fat known to generate heat when an animal is cold and generally considered to be " good ", interacted with the intestinal hormone to signal your fullness during a meal.

German and Finnish researchers have demonstrated the existence of a link between the intestine, brain and brown tissues and have unearthed the role until then unknown of the complex regulatory system in control of food intake.

"The vision of brown fat as a simple heating organ needs to be revised and more attention needs to be paid to its function in controlling hunger and satiety," said Martin Klingenspor, lead author of the paper, chair from the Department of Nutritional Nutritional Medicine University of Munich.

The intestinal hormone called secretin signals to the brain via the blood or nerves activated in the small intestine during a meal.

In the study on mice, scientists found that without brown fat, secretin could not produce the effect of suppressing appetite, suggesting that it is the only Effect of secretin on brown fat that causes the feeling of satiety.

In another study conducted in Finland on 17 human volunteers, oxygen consumption in brown tissues and the absorption of fatty acid were measured in the blood after a fasting night and 30 to 40 minutes after a meal.

The researchers found that higher levels of secretin in the blood of the subjects corresponded to a more metabolically active brown fat.

Klingenspor felt that the role played by brown fat in controlling hunger and satiety made it a particularly attractive target for new approaches to the treatment of obesity.

According to him, the targeting of brown fat by secretin could be a potential solution for future nutritional or pharmacological interventions against obesity and metabolic diseases.