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Scientists, including one of Indian descent, have discovered that night work increases the risk of developing obesity and diabetes, which can lead to heart disease, stroke and stroke. cancers.
University (WSU) in the United States, dispelled the belief that the day-night cycle of the body is driven by the master clock of the brain, and revealed that distinct biological clocks in the liver, l & # 39; 39, bowel and pancreas have a clean mind. [19659002] "Nobody knew that biological clocks in people's digestive organs are so deeply and quickly changed by shift work schedules, even though the main brain clock barely fits to times, "says Hans Van Dongen of WSU. "As a result, some biological signals in the bodies of shift workers say that it is daytime while other signals say that it is night, which causes a disruption of the metabolism," he said. he said. "We believe that ours is the first study to suggest a mechanism for the link between teamwork and chronic kidney disease," said WSU professor Shobhan Gaddameedhi.
The research also has implications for the study of other chronic diseases. Shift workers are inclined to include chronic kidney failure and breast cancer, skin and prostate cancer. The researchers however stated that it is very important to unravel the connection between shift work and mentality.
"It is possible that changes in the metabolism of shiftworkers are associated with an alteration in the activity of cellular processes that may be involved in" Once we understand these cellular processes, we could potentially identify the genes involved and use that knowledge to find ways to prevent cancer in shift workers, "he added.
study analyzed blood samples for metabolites – products of chemical reactions involved in digestion – from blood samples from 14 healthy volunteers who had just completed a simulated schedule or a simulated night schedule.
jet lag, 24-hour rhythms in digestive-related metabolites changed by 12 hours, even though the master biological clock in the brain of the participants h "Twenty-seven metabolites have followed a rhythm of 24 hours during simulated night and day schedules, "said Debra Skene, a professor at the University of Surrey in the UK.
] "Of these, 24 showed a dramatic change of pace of 12 hours following the simulated night work schedule, which was not observed after the day work schedule. She said that just three days after a night shift could disrupt metabolism. "" By pinpointing the disrupted metabolic pathways, we will be able to unravel the mechanisms behind shift work and metabolic disorders, "Skene said. 19659013] Follow @htlifeandstyle for more
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