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The brain scans, there is still much to discover about the subtleties of the human mind. To understand the region of the brain linked to Alzheimer's disease, scientists have managed to create the most detailed map or atlas of the memory bank of the brain, the hippocampus.
Created with the help of fluorescent tracers and 3D animation, the map presents in great detail the structures, nerve connections and functions of the hippocampus.
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"Like a new atlas, we have constructed the most detailed schematic of the hippocampus to date," said lead author of the study, Michael Bienkowski of the Keck School of Medicine's University of Southern California.
"With a better map, we can see each region and its operation. A better map is a resource that scientists can use to better understand the hippocampus and how its degeneration causes disease ", Bienkowski said.
rdmag.com
The human hippocampus lies at the base of the brain and is shaped like a hippocampus. It stores memories, helps regulate emotions and guides navigation by spatial processing.
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It is the first part of the brain altered by Alzheimer's disease and the degeneration of the hippocampus can cause epilepsy and other diseases.
Kateryna Kon
Scientists can use the new map of the hippocampus to administer genetically targeted drugs to specific neurons producing fewer side effects. said the senior author, Hong-Wei Dong, professor of neurology at the USC.
Scientists have long known the basic architecture of the hippocampus in four parts. But with the new map, scientists can show its subregions and how nerve cells interact within the structure.
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"This totally changes our understanding by combining a wiring diagram with the gene expression of the mouse hippocampus. We see it doing different things and it gives us a new way of understanding how it all works together. This should have a very deep and broad impact, " Bienkowski said.
With contributions from IANS
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