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Washington: For the first time, a vaccine has been designed to control three common pathogens of travelers' diarrhea.
A new study conducted by a chemist from the University of Guelph, Mario Monteiro, confirmed it.
Monteiro said his 3-in-1 approach to developing a new vaccine could save lives in developing countries, where the three common pathogens kill more than 100,000 children under the age of five every year.
The study is published in the journal Vaccine.
The study found that the conjugate vaccine binds pathogenic E. coli proteins to the sugars of Shigella and Campylobacter jejuni. These are the three insects that contribute mainly to the global spread of the disease.
In tests on mice, the vaccine confers immunity against the three pathogens. To date, no licensed vaccine has existed against any of these pathogens.
In 2009, Monteiro developed a sugar-based vaccine against campylobacter alone and is currently undergoing human trials.
"We are targeting three pathogens at the same time – instead of three injections, you may only need one," Monteiro said.
Monteiro added that more research is needed to determine the optimal amounts of protein and sugars in the vaccine to make it more effective.
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