Researchers discover new record that could potentially replace cannabis

A long time ago, a Swiss pharmacist came across a substance extracted from a strange mossy plant that was marketed online as a "legal price" (it was obvious that the research was aimed only at research). After conducting several pharmacological studies on the foam, they discovered that its active ingredients exerted a similar anti-inflammatory and analgesic effect, but greater than that of tetrahydrocannabinol (THC) contained in cannabis.

Although the concept is still in its infancy, researchers believe that it has all it takes to be a more effective medical option for marijuana. Japanese phytochemist Yoshinori Asakawa learned in 1994 that this liverwort (Radula perrottetii) – a unique foam in Costa Rica, Japan and New Zealand – produced a natural substance called perrottetinene (PET). He further discovered that PET is correlated with THC and that individual atoms are coupled in the same way, although they have an additional benzyl group and their 3D structure varies.

The main author of the study, Jürg Gertsch, said in a statement: "It is amazing that only two species of plants, separated by 300 million years of evolution, produce psychoactive cannabinoids. "

Scientists from the University of Bern in Switzerland are studying the effects of PET and its comparisons with its cousin, marijuana. As published in the journal Science Advances, they administered drugs to two groups of mice, one receiving an injection of THC and the other a PET injection.

PET rapidly triggered cannabinoid receptors in the brains of mice. In addition, compared with THC, PET had a stronger anti-inflammatory effect. Once again, the researchers were surprised to find that the mice became too far apart because they did not trigger cannabinoid receptors related to ecstatic ecstasy or profusion of THC.

Andrea Chicca, of the Institute of Biochemistry and Molecular Medicine of the University of Bern, said: "This natural substance has a lower psychoactive effect and, at the same time, it is able to". inhibit inflammatory processes in the brain.

The researchers hope that their work will pave the way for the curative use of PET, analogous to the use of THC in the treatment of various long-term illnesses. Although PET has experimented with a number of animal models, researchers have indicated that much research needs to be done before considering this foam as the next miracle drug.

Gretsch further added: "Basic research on biochemical and pharmacological mechanisms as well as controlled clinical studies are needed to conduct research on cannabinoids."

In the end, the team only hopes that pharmaceutical companies will manufacture the substance as a probable substitute for marijuana, which, although prescribed to relieve some ailments and legally recognized in some states, remains an illegal narcotics drug. US federal law.

Let's get in the air without really doing it!