Longer duration of breastfeeding reduces the risk of NAFLD in women



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Longer lactation time reduced risk of developing non-alcoholic fatty liver disease in mid-life in breastfeeding women, according to a recently published study Journal of Hepatology.

"Lactation and its benefits for the child have been widely studied for years," Veeral H. Ajmera, MD, from the University of California at San Diego, said in a press release for the study. "However, this new analysis contributes to the growing evidence that breastfeeding also offers significant benefits to the mother's health – namely, to protect her from the development of non-alcoholic fatty liver disease during her old age. . "

The CARDIA study involved 844 women with at least one birth and one lactation collected between 1985 and 1986. The researchers selected random participants for the trial and the only confounding risk factors associated with NAFLD included race. and BMI.

Women reported lactation duration ranging from 0 months to 1 month (32%), from more than 1 month to 6 months (25%) and over 6 months (43%).

At the 25th year of follow-up, 54 women met the NAFLD definition of computed tomography. Of those with NAFLD, 43% breastfed for 1 month or less, 30% for 1 month to 6 months and 28% for more than 6 months.

The prevalence of NAFLDs decreased as the duration of lactation increased from 8.3% for women breastfed at least one month to 7.7% for those breastfeeding for more than one month to 6 months, at 4 months. 2% of those breastfed over 6 months.

Women whose breastfeeding was longer also had a significantly lower BMI (P <0.04), homeostatic model evaluation of insulin resistance (P <0.01), triglycerides (P <0.01), total cholesterol (P = 0.04) and LDL cholesterol (P = .01).

Adjusted multivariate analysis for baseline BMI, race, and post-baseline parity showed that a lactation duration greater than 6 months compared to 1 month or less correlated with a significantly lower risk of NAFLD (OR = 0.46, 95% CI, 0.22-0.97).

According to Ajmera and colleagues, the relationship between duration of lactation and NAFLD could be an important lifestyle intervention to prevent fatty liver disease.

"These studies add to the growing list of potential long-term benefits of lactation for maternal health, including decreased risk of breast and ovarian cancer, metabolic syndrome, and cardiovascular disease." "Wrote the researchers. "The promotion of breastfeeding among parish women during the perinatal period may represent a unique opportunity to reduce the prevalence of NAFLD." – by Talitha Bennett

Disclosure: The authors do not report any relevant financial information.

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