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Although some people adopt the saying "bald is beautiful," for others, alopecia or excessive hair loss can cause stress and anxiety. Some studies have shown that stimulating the skin with lasers can help regrow hair, but the equipment is often bulky, consumes a lot of energy and is difficult to use in everyday life. Now researchers have developed a flexible and portable photostimulator that accelerates hair growth in mice. They report their results in ACS Nano.
Affecting millions of men and women worldwide, alopecia has several known causes, including heredity, stress, aging, and elevated male hormones. The most common treatments are medications such as minoxidil, corticosteroid injections and hair transplantation. In addition, irradiation of the bald area with a red laser can stimulate the hair follicles, resulting in cell proliferation. However, this treatment is often impractical for home use. Keon Jae Lee and his colleagues wanted to develop a flexible and sustainable photostimulator that can be worn on human skin.
The team fabricated an ultrathin network of flexible vertical light emitting diodes (μLEDs). The network consisted of 900 red μLEDs on a chip slightly smaller than a postage stamp and only 20 μm thick. The device used nearly 1,000 times less energy per unit area than a conventional phototherapeutic laser, and it did not heat enough to cause thermal damage to human skin. The bay was robust and flexible, supporting up to 10,000 cycles of bending and deformation. The researchers tested the ability of the device to repel shaved-back mouse hair. Compared with untreated or minoxidil injected mice, mice treated with the μLED patch for 15 minutes daily for 20 days showed significantly faster hair growth, a wider regrowth zone, and longer hair. .
More information:
Han Eol Lee et al. Trichogenic photostimulation using monolithic AlGaInP flexible vertical light-emitting diodes, ACS Nano (2018). DOI: 10.1021 / acsnano.8b05568
Abstract
Alopecia is considered an aesthetic, psychological and social issue in modern people. Although laser-induced cutaneous stimulation is used for hair removal treatment, such treatment has significant drawbacks, namely high energy consumption, large equipment size and limited use in life. daily. Here, we present a portable photostimulator for hair growth applications using high performance flexible red vertical light emitting diodes (f-VLED). The flexible LEDs at the microscopic scale have been efficiently manufactured thanks to a simple monolithic manufacturing process. Finally, trichogenic stimulation of a hairless mouse was performed using high performance red F-VLEDs with high thermal stability, device uniformity and mechanical durability.
Although some people adopt the saying "bald is beautiful," for others, alopecia or excessive hair loss can cause stress and anxiety. Some studies have shown that stimulating the skin with lasers can help regrow hair, but the equipment is often bulky, consumes a lot of energy and is difficult to use in everyday life. Now researchers have developed a flexible and portable photostimulator that accelerates hair growth in mice. They report their results in ACS Nano.
Affecting millions of men and women worldwide, alopecia has several known causes, including heredity, stress, aging, and elevated male hormones. The most common treatments are medications such as minoxidil, corticosteroid injections and hair transplantation. In addition, irradiation of the bald area with a red laser can stimulate the hair follicles, resulting in cell proliferation. However, this treatment is often impractical for home use. Keon Jae Lee and his colleagues wanted to develop a flexible and sustainable photostimulator that can be worn on human skin.
The team fabricated an ultrathin network of flexible vertical light emitting diodes (μLEDs). The network consisted of 900 red μLEDs on a chip slightly smaller than a postage stamp and only 20 μm thick. The device used nearly 1,000 times less energy per unit area than a conventional phototherapeutic laser, and it did not heat enough to cause thermal damage to human skin. The bay was robust and flexible, supporting up to 10,000 cycles of bending and deformation. The researchers tested the ability of the device to repel shaved-back mouse hair. Compared with untreated or minoxidil injected mice, mice treated with the μLED patch for 15 minutes daily for 20 days showed significantly faster hair growth, a wider regrowth zone, and longer hair. .
More information:
Han Eol Lee et al. Trichogenic photostimulation using monolithic AlGaInP flexible vertical light-emitting diodes, ACS Nano (2018). DOI: 10.1021 / acsnano.8b05568
Abstract
Alopecia is considered an aesthetic, psychological and social issue in modern people. Although laser-induced cutaneous stimulation is used for hair removal treatment, such treatment has significant drawbacks, namely high energy consumption, large equipment size and limited use in life. daily. Here, we present a portable photostimulator for hair growth applications using high performance flexible red vertical light emitting diodes (f-VLED). The flexible LEDs at the microscopic scale have been efficiently manufactured thanks to a simple monolithic manufacturing process. Finally, trichogenic stimulation of a hairless mouse was performed using high performance red F-VLEDs with high thermal stability, device uniformity and mechanical durability.
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