A report of chain reaction antibiotics failed in 22 of the 25 hamburger chains, including McDonald's.

The criticism is in progress. And here is the pharmaceutical data on your favorite hamburgers.

According to a recent collaborative report that ranked the 25 fast-food burgers in fast food restaurants for antibiotics, only two – Shake Shack and BurgerFi – received the "A" rating. Wendy's received a "D-" and the remaining 22 channels received an "F."

When farmers use antibiotics in animal agriculture, this increases the chances of spread of antibiotic-resistant bacteria, according to Lena Brook, acting director of the Natural Food and Agriculture Program. Resources Defense Council, which was one of the organizations involved. creating the report. The chain reaction report is produced for the fourth year by the Center for Food Safety, the Consumer Reports, the Trust Animal Concerns Trust, the US PIRG Education Fund, Friends of the Earth and the Natural Resources Defense Council. .

"Experts around the world are considering antibiotic resistance to antibiotics as one of the major threats to public health," Brook said. "When resistant bacteria spread from farms to communities, common infections that could previously be treated with antibiotics can become lives. threatening or even fatal ".

More: Burger King says his new Halloween creation "Nightmare King" can cause nightmares

More: National Pasta Day: Where to Find Pasta and Free Offers on Wednesdays

More: It's Duck Season: Arby's Serve A New Seared Duck Sandwich

BurgerFi CEO Corey Winograd said in a statement that the results of the report were "not a surprise" for the channel.

"We are known for providing a natural hamburger experience and we will continue our commitment to quality food products that guarantee the absence of steroids, antibiotics, growth hormones, chemicals or additives," Winograd said.

McDonald's – the largest beef buyer in the United States – received an F on the ballot. However, a company spokesman said that "preserving the effectiveness of antibiotics for future generations is very important for McDonald's".

"McDonald's is finalizing a global antibiotic policy for beef, which will be announced before the end of 2018," said McDonald's spokesman.

Wendy's got a "D-" because 15% of her beef comes from producers who reduced by one-fifth the use of tylosin, an antibiotic.

Here's how each of the 25 largest fast-food chains was ranked in the report: