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Vaping can be as bad for your lungs as conventional smoking, the scientists warned.
New research has claimed that aromas in electronic cigarettes, which help some smokers to quit smoking, damage the lungs by causing inflammation.
But even a short-term use causes as much or more damage than reality, revealed the team at the University of Athens.
In experiments on mice, they discovered that additives, including aroma, caused inflammation of the lungs similar or worse than that observed in the use of traditional cigarettes.
Dr. Constaninos Glynos said: "The adverse effects observed in the lung on the exposure of electronic cigarette vapors in animal models highlight the need for further research on the safety and toxicity of these rapidly expanding devices in the whole world".
Electronic cigarettes simulate the smoke of a traditional cigarette by dispensing a vapor derived from liquid chemicals into a refillable cartridge.
They usually contain propylene glycol, nicotine and often aromas.
Propylene glycol – a colorless and odorless additive – is found in many processed foods and beverages. It is also used as a solvent in a number of pharmaceutical products.
The results, published in the American Journal of Physiology-Lung Cellular, show that e-cigs and refills are not well regulated – and that their long-term health effects are unknown.
The researchers compared several groups of mice that had been exposed throughout the body to various combinations of chemicals four times a day, with each session separated by 30-minute smoke-free intervals.
Dr. Glynos said, "E-cigarettes are presented as a less harmful nicotine delivery system or as a new tool to quit smoking.
"Our results suggest that exposure to e-cig vapors can trigger inflammatory reactions and impair the functioning of the respiratory system.
"In many cases, the added flavor in e-cigs has exacerbated the damaging effects of e-cigs."
One group received cigarette smoke and three others e-cigarette vapors containing propylene glycol and nicotine, or both of these ingredients and a tobacco aroma.
A fifth batch comes to have normal and healthy air and serves as a control.
Some animals in each group underwent the diet for three days and others four weeks.
There was an increase in markers of inflammation, mucus production and alteration of lung function in the three groups of e-cigs – after only three days.
But those receiving propylene glycol alone have shown fewer negative effects in long-term exposure.
Dr. Glynos, from the University of Athens, said that this suggests that the additive causes only temporary irritation that eventually fades with use. keep on going.
In addition, two proteins producing inflammation increased in the group of flavors.
This means that some of the many flavoring ingredients on the market may not be safe even for short-term use, Dr. Glynos said.
The condition of the e-cigs groups alarmed the researchers. The level of oxidative stress – damage at the cellular level – in people exposed to the flavors was equal to or greater than that of the group of cigarettes.
More: United Kingdom
However, respiratory mechanics were only affected in mice exposed to cigarette smoke – and not to e-cig vapor after prolonged treatment.
Dr. Glynos added, "We conclude that electronic smoking and traditional smoking have a negative impact on lung biology."
According to figures from the Office for National Statistics, some 7.4 million Britons smoke and 2.8 million use electronic cigarettes.
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