According to studies, common painkillers have a dual risk of heart attack, stroke



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According to a new report, many people are looking for painkillers to get rid of headaches or reduce fever, but some of these common medications may increase the risk of heart disease or stroke.

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A researcher from the University Hospital of Aarhus in Denmark recently conducted a study, published in the British Medical Journal, to explore the cardiovascular risks associated with diclofenac, a traditional nonsteroidal anti-inflammatory drug (NSAID).

To do this, they used national registry data containing information on 6.3 million adults in Denmark. Participants, aged 46 to 56, were divided into low, moderate and high baseline cardiovascular risk groups and were followed for 20 years from 1996 to 2016.

They found that within 30 days of starting diclofenac, the rate of major adverse cardiovascular events, such as irregular heartbeats, ischemic sagging, heart failure, and heart attack, was higher than in other traditional NSAIDs .

In fact, the risk of having an adverse cardiovascular event was 50% higher in those who took diclofenac than in those who did not take it.


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In addition, they stated that there was also a relationship between diclofenac and an increased rate of cardiac death and upper gastrointestinal bleeding.

"The treatment of pain and inflammation with NSAIDs may be useful for some patients to improve the quality of life despite potential side effects," the team wrote. in a statement. "However, given its cardiovascular and gastrointestinal risks, there is little justification to initiate treatment with diclofenac before other traditional NSAIDs."

Scientists acknowledged that the study was observational. However, they noted that the size of their sample was larger than most previous analyzes on similar topics.

A 2018 study of 57,000 people in Taiwan, published in the British Journal of Clinical Pharmacology, found that some prescription painkillers, such as ibuprofen and naproxen, may be associated with an irregular heartbeat.

Another study published in March 2017, which analyzed nearly 30,000 patients, concluded that consumption of any type of NSAID, such as ibuprofen, could increase the risk of heart attack by 31%.



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