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An experimental vaccine against Alzheimer's disease may soon halve cases of dementia and delay the effects of degenerative brain disease by five years.
Researchers at the Southwestern Medical Center at the University of Texas at Dallas said the new vaccine had yielded promising results in recent animal testing and that he hoped the vaccine would be successful in trials. # 39; man.
The transition from animal testing to human use is long and arduous, and many promising remedies do not withstand it. But a senior author of the research published this week in the newspaper Alzheimer's Research and Therapy According to USA Today, if the vaccine proved safe and effective during human testing, it could halve the total number of diagnoses of dementia.
Alzheimer's disease is the most common cause of dementia, a term used to describe the symptoms of cognitive decline leading to memory, thinking and behavior problems.
The experimental vaccine marks a monumental advance in the fight against dementia, with earlier vaccines against Alzheimer's disease causing harmful side effects, including inflammation of the brain. Recent tests on monkeys and rabbits have shown that the vaccine works by inducing the body to produce antibodies that reduce the accumulation of amyloid and tau. Both proteins usually indicate the presence of a degenerative brain disease in the body.
Doris Lambracht-Washington, a professor of neurology and neurotherapeutics at Southwestern Medical Center at the University of Texas, told USA Today that the vaccine could prolong people's lives and prevent the disease from spreading through the brain.
"If the onset of the disease could be delayed even five years, it would be huge for patients and their families," Lambracht-Washington said. "The number of dementia cases could fall by half."
Two abnormal protein structures called plaques and tangles can accumulate in the brain and disrupt nerve cells. The new vaccine could possibly stop such an accumulation of these proteins without causing autoimmune inflammation, the researchers wrote.
According to the Alzheimer's Association, this disease is the sixth leading cause of death in the United States. About 5.7 million Americans currently live with Alzheimer's disease and researchers predict that this number will reach 14 million by 2050. Between 2000 and 2015, deaths related to Alzheimer's disease 39, Alzheimer's increased by 123 percent.
Ruth Itzhaki, Professor in the Division of Neuroscience and Experimental Psychology at the University of Manchester, UK, said Newsweek Last month, a commonly transmitted herpes virus could be causing 50% of Alzheimer's disease cases. According to the World Health Organization, about 3.7 billion people under the age of 50, about 67 percent of the world's population, have herpes simplex virus type 1 in their bodies.
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