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The error bars are 95% uncertainty intervals. Greece did not release data on S pneumoniae isolates to the European Antimicrobial Resistance Surveillance Network in 2015. DALY rates are standardized for age, in order to limit the risk of malaria. effect of demographic differences from one country to another. the number of cases and deaths is not normalized according to age. DALY = life years adjusted for disability. * Does not include carbapenem or colistin resistant. † In 2015, most of the isolates from E. Cephalosporin resistant cephalosporin resistant cephalosporin (88.6%) and cephalosporin (88.3%) were reported to the European Antimicrobial Resistance Surveillance Network and resulted in an extended spectrum β-lactamase . Credit: ECDC / TLID
A study by the ECDC estimates the burden of five types of infections caused by antibiotic-resistant bacteria of public health concern in the European Union and the European Economic Area (EU / EEA). The burden of illness is measured in number of cases, attributable deaths and disability adjusted life years (DALYs). These estimates are based on data from the 2015 European Antimicrobial Resistance Surveillance Network (EARS-Net) data.
The authors stated: "The estimated burden of infections by antibiotic-resistant bacteria in the EU / EEA is substantial compared to that of other infectious diseases and has increased since 2007. Prevention and control strategies are Control of antibiotic-resistant bacteria requires coordination at EU / EEA level Our study however showed that the contribution of various antibiotic-resistant bacteria to the overall burden varied considerably from country to country. another, emphasizing the need for prevention and control strategies adapted to the needs of each EU / EEA country. "
The study estimates that about 33,000 people die each year from direct consequences of an infection with an antibiotic-resistant bacterium and that the burden of these infections is comparable to that of influenza, tuberculosis and HIV / AIDS combined. This also explains that 75% of the disease burden is due to healthcare-associated infections and that reducing it through appropriate infection prevention and control measures, as well as antibiotic management, could be a feasible goal. in health care facilities.
Finally, the study shows that 39% of the load is caused by infections with bacteria resistant to the last-line antibiotics, such as carbapenems and colistin. This is an increase from 2007 and is of concern as these antibiotics are the last available treatment options. When these are no longer effective, it is extremely difficult, if not impossible, to treat infections.
Explore further:
Superbugs killed 33 000 Europeans in 2015: study
More information:
Alessandro Cassini et al, Attributable deaths and disability adjusted life years and caused by infections by antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a modeling analysis at the level of the population, The Lancet Infectious Diseases (2018). DOI: 10.1016 / S1473-3099 (18) 30605-4
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