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Researchers say that skin cancer could be one of the applications of patches.
"This means that eight or nine silicon nanoneedles can be injected into a single cell without significantly damaging a cell, so we can use these nanoneeds to deliver biomolecules into cells or even tissues with a minimum of invasion. "said Chi Hwan Lee, assistant professor at Purdue. University.
Nanoneedle silicon patches are currently placed between the skin, muscles or tissues where they deliver exact doses of biomolecules.
Commercially available silicon nanoneedle patches are typically constructed on a rigid, opaque silicon wafer.
Stiffness can cause discomfort and can not stay long in the body.
"These qualities are exactly opposite to the flexible, curved and soft surfaces of biological cells or tissues," Lee said, adding that they had now solved this problem.
"We have developed a method that allows the physical transfer of silicon nanoneedles vertically ordered from their original silicon wafer to a bio-patch," Lee said.
This nanoneedle patch is not only flexible but also transparent and can therefore also allow simultaneous real-time observation of the interaction between cells and nanoneedles, said the study published in the journal Science Advances.
Teams from Hanyang University (South Korea) and the Weldon School of Biomedical Engineering in Purdue and the School of Mechanical Engineering received joint support from the Office of Scientific Research of the Army of American air and the Korean Ministry of Science and ICT to carry out this study.
The researchers hope to develop the functionality of the patch for it to act as an external skin patch, reducing the pain, invasiveness and toxicity associated with long-term drug delivery.
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