Can milk proteins mitigate the side effects of chemotherapy?



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A recent study suggests that milk proteins can mitigate the side effects of chemotherapy.

The study suggests that chemotherapy and other anti-cancer treatments can wreak havoc on taste buds and olfactory senses, depriving recipients of the complex interaction between taste and smell that is essential to capturing flavors and flavors. appreciate the food. Over time, taste and odor abnormalities (ASD) can lead to loss of appetite and anorexic behavior, compromising patients' ability to recover from the disease.

Researchers investigated the feasibility of lactoferrin, a highly bioactive protein found in saliva and milk, as a treatment for ASD.

Duncan, one of the lead researchers said: "The underlying molecular mechanisms of TSA are not well understood.The dominant symptom described by patients undergoing chemotherapy is a persistent metallic taste or aftertaste, with or without food intake weeks or even months after the end of treatment. "

As a result, cancer patients suffer from a lack of appetite, weight loss, depression and a decrease in nutrition, which is detrimental to their health. recovery. Although ASD is widespread and cancer patients frequently complain, there is no established treatment to date to reliably prevent or treat this problem.

"Our research shows that daily supplementation with lactoferrin induces changes in salivary protein profiles in cancer patients – changes that may influence taste protection and odor perception," Duncan said.

"By suggesting lactoferrin as a dietary supplement, we can reduce ASD in many patients, allowing them to better appreciate foods at a time when nutrition can play a key role in their recovery," he added.

According to the researchers, this study could help us develop targeted biomarkers for ASD and strategies to improve the quality of life during chemotherapy. "Cancer patients and their families and friends who support them can still find solace by enjoying a meal together," Duncan said.

The team believes that their results will allow cancer patients to taste food properly and enjoy a healthier appetite, thus enabling optimal nutrition during a critical recovery period. Lactoferrin supplementation also enhances the expression of salivary immune proteins, which can help reduce oxidative stress and the resulting side effects. Oral infections, such as lily of the valley, can also be diminished.

The results appeared in the Journal – Food & Function.

(This article has not been modified by Business Standard staff and is generated automatically from a syndicated feed).

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