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Mainly because of exposure to radiotherapy, people who survived childhood cancer may be at increased risk of developing hormonal disorders that may lead to thyroid disease, testicular dysfunction, and diabetes. To warn health care providers of these risks, the Endocrine Society, an international medical organization, published this week a "Clinical Practice Guideline" that was published in the Journal of Clinical Endocrinology and Metabolism (JCEM).
"Survivors of childhood cancer have a high risk of developing endocrine disorders," said Charles Sklar of the Memorial Sloan Kettering Cancer Center in New York, who chaired the writing committee that developed the guideline . which make hormones that help control many important functions of the body, including the regulation of blood sugar.
Childhood cancer is relatively rare, and with improvements in treatment and patient care, current five-year survival rates exceed 80%.
However, these survivors also face a greater risk of developing sleep problems and daytime sleepiness than adults and hypertension, even decades after the end of cancer treatment.
Endocrine disorders are particularly common in this population, often because of their previous treatments, particularly exposure to radiotherapy .
Radiation exposure of major endocrine organs including the hypothalamus, pituitary gland, thyroid and gonads. Cancer survivors at highest risk of developing an endocrine abnormality over time.
Recent data show that almost 50 percent of these survivors will develop an endocrine disorder during their lifetime.
These diseases can develop decades after cancer treatment, highlighting the importance of lifelong surveillance, researchers said.
This recommendation provides recommendations for the diagnosis and management of certain endocrine disorders and growth in childhood cancer survivors.
She recommends long-term screening of childhood cancer survivors for growth disorders, pituitary deficits, and precocious puberty.
"Our new guideline addresses the increasing risk of endocrine disorders in childhood cancer survivors and highlights the importance of screening these survivors throughout their lives for early detection and optimal patient management. ". 19659002] sh / rt / gb / ksk
(This story was not edited by Business Standard staff and is generated automatically from a syndicated feed.)
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