Effective Weight Loss Drug for Remission of Diabetes: Study

New York, Oct. 5 (IANS) Lorcaserine – a slimming drug – can help reduce the risk of diabetes, induce remission and reduce the risk of diabetes complications in obese and overweight patients, according to a study.

Researchers at Brigham and Women's Hospital (BWH) found that lorcaserine reduced the risk of diabetes by 19% in patients with pre-diabetes, diabetic neuropathy – a type of nerve damage that can occur with diabetes – 21%.

It has also resulted in remission of hyperglycemia in diabetics and reduced the risk of diabetic microvascular complications such as microalbuminuria – moderate increase in albumin levels in the urine.

Earlier, researchers discovered that "the use of lorcaserine has resulted in modest but sustained weight loss in overweight and obese patients without increased risk of heart attack or stroke," he said. said Erin Bohula of the BWH.

"Now, we report that, when added to lifestyle-enhancing interventions, Loracerin significantly reduced the incidence of diabetes, increased the rates of diabetes remission and reduced the risk of complications." diabetic microvascular, "Bohula added.

For the study, published in The Lancet, the team randomly assigned 12,000 overweight or obese patients at risk of cardiovascular events to receive lorcaserin or placebo.

The results showed that 9.5% of patients were able to reach normal glycemic levels.

Lorcaserin also significantly increased the rate of remission of hyperglycemia in diabetic patients, with 7.1% of patients on medication achieving remission compared with 6% of patients on placebo.

Lorcaserin also helped patients reduce their weight by 4.2 kg on average, compared with 1.4 kg for placebo at one year.

"Taken together, these findings reinforce the idea that modest and lasting weight loss can improve cardiometabolic health and reinforce the role of lorcaserine as adjunctive therapy in chronic weight management." "said Benjamin Scirica, of the hospital.

–IANS

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