Europe: antibiotic-resistant bacterial infections linked to 33,000 deaths a year



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A study published in The Lancet Infectious Diseases estimates that about 33,000 people die each year as a direct result of infection with an antibiotic-resistant bacterium and that the burden of these infections is comparable to that of influenza, tuberculosis and HIV / AIDS. combined.

The error bars are 95% uncertainty intervals. Greece did not report data on S pneumoniae isolates to the European AMR surveillance network in 2015. DALY rates are standardized for age to limit the effect demographic differences between countries; the number of cases and deaths is not normalized according to age. DALY = life years adjusted for disability. * Does not include patients resistant to carbapenem or colistin. † In 2015, most of the isolates from E. Cephalosporin resistant cephalosporin-resistant (88.6%) and cephalosporin-resistant K pneumoniae (88.3%) reported to the European Network for the Surveillance of Antimicrobial Resistance Agents produced a broad-spectrum β-lactamase. Image / ECDC / TLID
The error bars are 95% uncertainty intervals. Greece did not report data on S pneumoniae isolates to the European AMR surveillance network in 2015. DALY rates are standardized for age to limit the effect demographic differences between countries; the number of cases and deaths is not normalized according to age. DALY = life years adjusted for disability. * Does not include patients resistant to carbapenem or colistin. † In 2015, most of the isolates from E. Cephalosporin resistant cephalosporin-resistant (88.6%) and cephalosporin-resistant K pneumoniae (88.3%) reported to the European Network for the Surveillance of Antimicrobial Resistance Agents produced a broad-spectrum β-lactamase.
Image / ECDC / TLID

This also explains that 75% of the disease burden is due to healthcare-associated infections and that reducing it through appropriate infection prevention and control measures, as well as antibiotic management, could be a feasible goal. in health care facilities.

Finally, the study shows that 39% of the load is caused by infections with bacteria resistant to the last-line antibiotics, such as carbapenems and colistin. This is an increase from 2007 and is of concern as these antibiotics are the last available treatment options. When these are no longer effective, it is extremely difficult, if not impossible, to treat infections.

The burden of illness is measured in number of cases, attributable deaths and disability adjusted life years (DALYs). These estimates are based on data from the 2015 European Antimicrobial Resistance Surveillance Network (EARS-Net) data.

According to researchers at the European Center for Disease Prevention and Control (ECDC), "the estimated burden of infections by antibiotic-resistant bacteria in the EU / EEA is substantial compared to that of other infectious diseases and has increased since 2007. Strategies for prevention and control of antibiotics Virus-resistant bacteria require coordination at EU / EEA and global level.

"However, our study has shown that the contribution of various antibiotic-resistant bacteria to overall burden varies considerably from country to country, highlighting the need for prevention and control strategies tailored to the needs of the population." each country of the EU / EEA ".

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