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The largest study of the genetic makeup of parasitic worms has found hundreds of new clues about how they invade the human body, its immune system and cause disease.
The results of this study may be of interest to you, but you may also be interested in some of the most common tropical diseases – including river blindness, schistosomiasis, and hookworm disease – which affect around a billion people worldwide.
"These are some of our oldest and most important experts in the human immune system," said Makedonka Mitreva of Washington University's McDonnell Genome Institute, who co-led the work with colleagues from Britain's Wellcome Sanger Institute. and Edinburgh University.
She said that the results of this study would lead to a deeper understanding of the biology of parasites and a better understanding of how human immune systems can be harnessed or controlled.
Parasitic worm infections can be severe, physical disabilities, retarded development in children and social stigma linked to deformity.
Sanofi, GSK, and Johnson & Johnson – can be moderately effective and are often used by drug manufacturers. But the spectrum of drugs to treat infections is still limited.
Too much of the genetics of the genome of the genome of the genome of the genome.
The analysis found almost a million new genes, and many new potential drug targets and drugs.
"Said the Sanger Institute's April Coghlan, who worked on the team. She said this offered a fast-track route to "pinpointing existing drugs that could be repurposed for deworming."
The study's findings were published Monday in the journal Nature Genetics.
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