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Last Updated: October 30, 2018.
The Alzheimer's Association has released appropriate-use criteria for lumbar puncture and cerebrospinal fluid testing in Alzheimer's disease diagnosis, according to a review article published online Oct. 10 in Alzheimer's & Dementia.
TUESDAY, Oct. 30, 2018 (HealthDay News) – The Alzheimer's Association has released appropriate-use criteria for lumbar puncture and cerebrospinal fluid (CSF) testing in Alzheimer's disease diagnosis, according to a review article published online Oct. 10 in Alzheimer's & Dementia.
Leslie M. Shaw, Ph.D., from the University of Pennsylvania in Philadelphia, and colleagues report on the Alzheimer's Association of a multidisciplinary workgroup to develop appropriate use of the procedure testing for Alzheimer 's disease pathology detection in the diagnostic process. The workgroup developed in clinical trials in clinical trials and in clinical trials.
The workgroup finalized 14 indications, rating six appropriate and eight inappropriate. The appropriate indications include: subjective cognitive decline and increased risk for Alzheimer's disease; persistent, progressive, and unexplained mild cognitive impairment; suggestive of possible symptoms Alzheimer's disease; mild cognitive impairment or dementia with onset at an early age (<65 years); meeting core clinical criteria for probable Alzheimer's disease with typical age of onset; and having a dominant symptom of unexplained change in behavior with an Alzheimer 's disease diagnosis being.
"In anticipation of the emergence of more reliable CSF analysis platforms, the manuscript offers important guidance to health care practitioners and suggestions for implementation and future research," write the authors.
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