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TUESDAY, Oct. 30, 2018 (HealthDay News) – The Alzheimer's Association has published appropriate criteria for use in lumbar puncture and cerebrospinal fluid (CSF) tests for the diagnosis of Alzheimer's disease, according to an article summary published online on October 10 Alzheimer's and dementia.
Leslie M. Shaw, Ph.D., of the University of Pennsylvania at Philadelphia, and colleagues report the convening by the Alzheimer's Association of a multidisciplinary task force tasked develop appropriate use criteria to guide the safe and optimal use of the lumbar puncture procedure and CSF. Detection tests for the pathology of Alzheimer's disease in the diagnostic process. The working group developed key research questions to guide the systematic review of evidence and developed clinical indications commonly encountered by clinicians based on key patient groups for which lumbar puncture and CPAP could be considered in the study. the diagnostic process.
The working group has developed 14 indications, six appropriate and eight inappropriate. Appropriate indications include: subjective cognitive decline and increased risk of Alzheimer's disease; persistent, progressive and unexplained mild cognitive impairment; symptoms suggestive of possible Alzheimer's disease; mild cognitive impairment or dementia appearing early (under 65 years of age); meeting the basic clinical criteria of probable Alzheimer's disease with typical age of onset; and having a dominant symptom of unexplained behavior change with a diagnosis of Alzheimer's disease under study.
"In anticipation of the emergence of more reliable CRL analysis platforms, the manuscript offers important advice to health practitioners and suggestions for future implementation and research," write the authors.
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