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Men struggling in the bedroom can now blame their genes, according to new research.
For the first time, scientists have discovered a confirmed genetic link to erectile dysfunction.
The researchers spotted a segment of DNA whose variations made men more difficult to perform than expected.
The suspicion finger points to a gene called SIM1 that could be a target for new treatments against impotence.
The lead researcher, Dr. Eric Jorgenson, of Kaiser Permanente, a US provider of health services, said: sickness.
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"The identification of the first genetic risk factor for erectile dysfunction is an exciting discovery because it opens the door to investigations of new genetic-based treatments."
In addition to having a potential influence on men's erections, SIM1 is thought to play a role in brain development.
Scientists conducted this study by analyzing the complete genomes, or genetic codes, of more than 36,000 Americans and 222,000 Britons.
Research was done on genetic differences that occurred more often in men with a history of erectile dysfunction.
Variations in the SIM1 locus, the region of the DNA containing the SIM1 gene, were associated with an increased risk of impotence of 26%.
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Erectile dysfunction has several known physical causes, including hormonal deficiencies and nerve and arterial damage.
But despite the effectiveness of treatments such as Viagra, many men can not be helped.
Scientists believe that a genetic "promoter" that turns SIM1 on and off can explain their findings rather than the gene itself.
The search is reported in the newspaper Proceedings of the National Academy of Sciences.
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