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There are several plants that contain a pain substance similar to cannabis, ScienceNews has reported. Swiss researchers have revealed that the hepatic is an almost equal alternative to medical cannabis.
The benefits of medicinal cannabis are obvious, but other herbs have a similar analgesic effect, according to researchers at the University of Bern and the ETH Zurich Institute of Technology. Pharmacologists believe that the perrotetinene compound (PET) present in some liverworts may be a better alternative to cannabis. Unfortunately, liverworts grow only in Japan, Costa Rica and New Zealand.
The psychoactive effects of PET resemble THC, the active ingredient in cannabis, according to Japanese scientists who first discovered perrotetinene in liverworts. Despite this, a Swiss study is the strongest evidence to date that the compound is a psychoactive cannabinoid. Their results show the compound of the Radula perrottetii Hepatic easily binds to cannabinoid receptors in the brain and may reduce the sensation of pain.
The cannabinoid derived from the hepatic is an analgesic even more powerful than cannabis
Pharmacologists have stated that PET even has a stronger anti-inflammatory effect than THC and that its potential medical applications have a bright future. In addition, the compound of Radula perrottetii has the advantage of being legal and having less psychoactive effect than THC.
To study the effects of PET, Swiss scientists needed a large amount of substance and asked their colleagues at ETH Zurich to synthesize a sufficient amount of THC and PET to perform tests on mouses.
To solve this problem, they called on colleagues at ETH Zurich, who synthesized the THC and PET needed to perform tests on mice.
"This study is a prime example of how new synthetic concepts can enrich our pharmacological knowledge of biologically active natural substances," said ETH PhD candidate Michael Schafroth.
Until now, in Switzerland, Sativex is the only cannabis-based drug on the market.
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