Reduced risk of death from colon cancer in soft drinkers



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New research finds association between drinking artificially sweetened beverages and significantly lower risk of recurrence of colon cancer and cancer deaths

"Sweetened beverages have a public reputation for alleged health risks never documented, "says lead author Charles S. Fuchs, director of the Yale University Cancer Center. "Our study clearly shows that they help prevent recurrence of cancer and death in patients who have been treated for advanced colon cancer."

"… in terms of recurrence and survival of colon cancer, use of artificially sweetened beverages Fuchs and his team of researchers found that in the analysis of 1,018 patients, participants who drank a or several 12-ounce portions of artificial sweetener are not a health risk. Drinks per day have experienced a 46% improvement in the risk of cancer recurrence or death, compared to those that do not. The researchers defined these soft drinks as caffeinated colas, colas without caffeine and other soft drinks (such as ginger ale).

A second analysis revealed that about half of this benefit was attributable to an artificially sweetened drink. "Although the association between recurrence of lower colon cancer and death was a little stronger than we suspected, the discovery corrected responds to everything we know about the risk of colon cancer in general, "says Fuchs. "Factors such as obesity, sedentary lifestyle, diet-related diabetes – all of which lead to excess energy balance – are known risk factors. We now find that in terms of recurrence and survival of colon cancer, the use of artificially sweetened beverages is not a health risk, but is, in this study, a healthier choice. "

" … a change in lifestyle – drinking artificially sweetened beverages – changing cancer outcomes after surgery? "

This research closely follows a number of studies that prospectively followed patients with stage III colon cancer enrolled in a National Cancer Institute." Supported clinical trials testing two different forms of postoperative chemotherapy

Participants completed full nutrition questionnaires examining the consumption of over 130 different foods and beverages for several months, a questionnaire was administered when patients underwent chemotherapy between 1999 and 2001, and again Six months after the end of chemotherapy, the researchers tracked cancer recurrence and patient mortality rates for about seven years, concluding, among other things, that the two chemotherapy regimens offered fair benefits. [19659002] The researchers designed the studies included in the global clinical trial. s between specific foods / drinks and the risk of colon cancer and death. They were not meant to prove the cause and the final effects.

A study found that clinical trial participants who drank coffee had a significantly reduced risk of cancer recurrence and death. Another found a similar benefit in patients who ate nuts. This study focused on artificially sweetened beverages because an earlier study had concluded that sugary drinks dramatically increased the risk of developing colon cancer. "We wanted to ask the question if, after the development and development of cancer, a change in lifestyle Cancer cells adapt to the throats of sugar in the liver

He adds that the impact on the health of these soft drinks deserves to be studied: sweeteners can increase the incidence of obesity, diabetes and cancer, but studies on issues like weight gain and diabetes have been very mixed and, with regard to cancer, epidemiological studies in humans have not demonstrated such relationships. "

The study appears in PLOS ONE . The National Institutes of Health's National Cancer Institute supported the research in part. Pharmacia & Upjohn Company, now Pfizer Oncology, and the American Institute for Cancer Research have provided additional support

One Missing Atom Can Result in Colon Cancer

Non-Federal Promoters Have Not Supported participated in the design and conduct of the study; collection, management, analysis and interpretation of data; preparation, revision or approval of the manuscript, or decision to submit the manuscript for publication.

Source: Yale University

Original Study DOI: 10.1371 / journal.pone.0199244

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