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Consuming a ketogenic diet – high levels of lipids and carbohydrates – can help prevent cognitive decline, according to a new study on mice.
The findings, published in the journal Frontiers in Aging Neuroscience, have shown that the stomach and brain are more closely related than previously thought and that the health of one can affect the other.
"Recent scientific research suggests that bacterial integrity may be regulated by intestinal bacteria, so we investigated whether the ketogenic diet improves cerebrovascular function and reduces the risk of neurodegeneration in healthy young mice" said Ai-Ling Lin, of the University of Kentucky in the United States.
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"Neurovascular integrity, including cerebral blood flow and blood-brain barrier function, plays a major role in cognitive abilities," Lin added.
For the study, the team examined the effect of the diet on cognitive health in the mouse, which was following a ketogenic diet.
Two groups of nine mice aged 12 to 14 weeks received either the ketogenic diet or a regular diet.
The team found that after 16 weeks, cerebral mice had significantly increased cerebral blood flow, that the gut microbiome was better balanced, that its blood glucose and body weight were lower, and that its process of releasing the brain – a hallmark of Alzheimer's disease.
"While diet changes, including the ketogenic diet, have proven effective in treating certain diseases, we have chosen to test healthy young mice using the diet as a potential preventative measure," Lin said. .
"We were excited to see that we could actually use a diet to mitigate the risk of Alzheimer's disease," Lin said.
| Edited by: Naqshib Nisar
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