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A Dutch medical team administered Sindenafil, a generic of the Erectile Dysfunction molecule to more than 90 pregnant women, whose babies were had developmental problems due to poor blood circulation in the placenta, as part of a trial for clinical purposes.
The goal was to take advantage of the features of this drug as vasodilator to improve blood flow in the placenta and thus create conditions for a better development of the baby in the womb.
However, the research did not give the expected results, since there were a total of 93 babies in whom this test was performed 17 had lung problems and 11 others died
One of the hypotheses is that the drug caused an increase in blood pressure, which caused the babies to receive less oxygen than they should. But these effects can only be brought to light once the child born
The trial ended last week when an independent committee, which oversaw the research, discovered that more babies were born than expected with lung problems.
10 and 15 pregnant women who have intervened, are still waiting for the birth of their children, which is not known with certainty what will be the state of health.
The research was promoted by the University Medical Center of Amsterdam (UMC) began in 2015 and is expected to involve 350 women by 2020.
A spokesman for the University of UMC said that he thought the experiment had been conducted properly, despite this, he expects the external investigation of the case begins. ] In this survey, hospitals in Canada, the United Kingdom and New Zealand were added. The last two reported that they had found no positive or negative effects on the placenta for the use of this drug.
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A Dutch medical team administered Sindenafil, a generic of the erectile dysfunction molecule to more than 90 pregnant women, whose babies had developmental problems due to poor blood circulation in the placenta, in the framework of a clinical trial
The goal was to take advantage of the features of this drug as vasodilator to improve blood circulation in the placenta and thus create the conditions for a better development of the baby in the womb.
However, the research did not yield the expected results, since there were a total of 93 babies in which this test was conducted, of which 17 had lung problems and 11 others died.
One of the hypotheses is that the drug caused an increase in blood pressure, which allowed the babies to receive have less oxygen than they should, but these effects only they can show once the child born
The trial ended last week when a Independent committee, which oversaw the research, discovered that more babies were born than expected with lung problems.
Even between 10 and 15 pregnant women those who intervened, are still waiting for the birth of their children, which is not known for sure what will be the state of health.
The research was promoted by the University Medical Center of Amsterdam (UMC) began in 2015 and it is expected to involve 350 women by 2020.
A spokesman for the University of UMC said that he thought the experiment had been conducted properly, despite this, he expected to start the respective external investigation of the case.
They reportedly added hospitals in Canada, the United Kingdom and New Zealand. The latter two reported that they had found no positive or negative effects on the placenta for the use of this drug.