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Eat a diet high in fat in short periods of time, between three and seven days, produces a increase of endocannabinoids in the hypothalamus, a region of the brain that controls the appetite and metabolism of the body, as well as the activity of brown fat, which promotes the expenditure of calories and helps to lose weight.
This has been demonstrated by a study conducted by the Neurolipid Research Group of the Faculty of Medicine and Health Sciences of the UIC Barcelona and published in the journal "Journal of Lipid Research & # 39 ;.
"With this study in mice, we found that the signal between endocannabinoids and brown fat occurs only when obesity is initial and not at an advanced stage of pathology.
In addition, we found that when these fats are ingested for short periods, the differences are produced by sex. The levels of endocannabinoids detected are higher in women and therefore have a greater greater protection against obesity than men", explained the scientists.
"The results of the study open the door to further exploration of endocannabinoids and activation of brown fat with early alterations of the hypothalamus, and to their consideration as a new biomarkers of obesity.
When the consumption of fatty foods is prolonged, from 28 days, researchers have detected a significant decrease in endocannabinoids, especially when it comes to an already established obesity.
In addition, it will approach this pathology in a different way taking into account the sex of the person, "they added.
Therefore, he continues, knowing that this dynamic of functioning will be the key to reach a potential prevention of progression of obesity and will help other cannabis experts and endocannabinoids for proper therapeutic use, with minimal side effects in the approach to obesity and diabetes-related conditions.
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