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This was determined in a clinical trial published in the New England Journal of Medicine, reports CNN.
"This is only the first step and opens the door to several new trials," says Dr. Matthias Gromeier, co-author of the study and professor of neurosurgery at the School of Medicine. Medicine of Duke University.
After testing this experimental therapy with animals, scientists started in 2012 to treat humans.
Among 61 patients with recurrent glioblastoma treated with poliovirus, 21% survived for three years or more – 12.5 months – compared to 4% after several chemotherapy sessions.
The virus is introduced into the tumor through a catheter for six and a half hours; with higher doses, some patients suffered from inflammation, seizures, cognitive impairment and nausea, among other things. The next step in the study is to treat patients with melanoma and breast cancer.
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