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"About 60 or 70% of women with breast cancer will have a cancer subtype associated with endocrine therapy or hormone receptor-positive therapy.This has led to the development of new therapies," said Dr. Gabriela Regalado in an interview with Efe
According to figures from the World Health Organization (WHO), cancer is the leading cause of death in the world.
On the scale worldwide, this disease kills more than eight million people each year and at least 90% of all cancer deaths are caused by metastases, that is, when cancer cells invade others. organs.
"Currently, the treatment is designed for women who develop metastatic disease. They may be premenopausal women, or postmenopausal women in combination with another treatment, and this (new) drug has shown substantial improvement, "said the specialist in Internal Medicine and Oncology at the ABC Medical Center.
Innovation more targeted therapies, less toxic and above all improve the quality of life and survival of patients, allowing them even incorporation into their daily tasks.
"These are drugs that allow patients to Have an adequate quality of life; the hair does not fall, there is no nausea-vomiting, the profile of toxic effects is very slight, which is different from the systemic chemotherapy we are used to, "said Regalado.
% of initial diagnoses of cancer are completely advanced or metastatic, so it is necessary to ensure a better quality of life "or a better result."
He noted that new pharmacological therapies, if combined with treatment endocrine, "improve progression-free survival of metastatic cancer."
This, he says, controls the disease to such an extent that it serves women who may be in metastatic stages, with disseminated disease or even in those who die, help them to have a better result.
New therapies, according to the specialist, inhibit two proteins called kinases "which are overactivated when there is ac r and this allows the cancer cells to grow and divide rapidly. "
Thus, the drug blocks these proteins and helps the cancer cells to not replicate.
For the doctor, change the conventional treatments such as chemotherapy for less aggressive, it gives the patient the" hope of having an adequate quality of life, "a better profile of toxicity, better control and response".
Although in the stages where this drug acts it is no longer possible to cure cancer, these New therapies help patients not to suffer typical symptoms related to the disease, such as bone pain, shortness of breath and tiredness.
"Having these therapies that can improve the outcome makes us go off to gain more time to develop new drugs that help us to eradicate cancer in its infancy and, if the metastatic disease is already there, we can manage to control it by many hos años, "he concluded
Ribociclib was approved in Mexico last November by the Federal Commission for the Prevention of Health Risks (Cofepris)
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