Where Men Store Fat Could Affect the Risk of Aggressive Cancer of the Prostate | Life



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According to new research, men who tend to store fat around the abdomen might have a higher risk of advanced prostate cancer. - Photo Oktay Ortakcioglu / Istock.com via AFP
According to new research, men who tend to store fat around the abdomen might have a higher risk of advanced prostate cancer. – Photo Oktay Ortakcioglu / Istock.com via AFP

BOSTON, June 11 – New research has revealed that the distribution of adipose tissue in humans could affect the risk of aggressive prostate cancer.

Conducted by researchers from the Harvard TH Chan School of Public Health, in collaboration with the National Institute of Aging, Bethesda (Maryland), the University of Iceland, the Icelandic Cancer Society and the Icelandic Cancer Registry, the new study involved 1,832 men and assessed their risk of being diagnosed or dying from prostate cancer.

The researchers also measured the body mass index (BMI) of the participants and analyzed the body fat distribution using a computer tomography reference measurement.

The participants were then followed for 13 years.

The results, published online in the journal CANCER, showed that visceral fat, that is, the abdominal fat that surrounds the organs, was associated with a higher risk of advanced prostate cancer, while subcutaneous fat from the thigh, present in the thighs just under the skin, was associated with a higher risk of prostate cancer.

The existence of a body mass index (BMI) and a higher waist circumference was also associated with an increased risk of advanced and fatal prostate cancer.

In addition, the team found that men with a leaner BMI, but with visceral fat, also had a higher risk of advanced disease and death.

"Interestingly, when we examined men with high BMI separately compared to low BMI, we found that the association between visceral fat and advanced and fatal prostate cancer was stronger in men. having a lower BMI. The accuracy of these estimates was limited in this subgroup analysis, but it is an intriguing signal for future research, "commented lead author Barbra Dickerman, PhD.

The team notes that the World Cancer Research Fund says there is "solid evidence" of a link between obesity and the risk of advanced prostate cancer. They add that further research is now needed to determine how the distribution of fat and its evolution over time can also affect the disease.

"Ultimately, identifying the fat distribution patterns associated with the highest risk of clinically significant prostate cancer can help elucidate the mechanisms linking obesity to aggressive disease and targeting men for strategies." of intervention, "Dickerman said. – AFP-Relaxnews

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