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3D printing is increasingly used in many areas, medical science is not left behind. From more traditional uses such as printing medical equipment and prosthetics to more advanced uses like cartilage and bone printing, the success of 3D printing technologies in the medical field is growing rapidly.
One of the latest breakthroughs is the world's first 3D vascularized artificial heart using the patient's own cells and biological material. Until now, scientists have managed to print only simple tissues without blood vessels. Researchers at Tel Aviv University used the adipose tissue of patients to separate cellular and acellular materials and reprogrammed the cells to become pluripotent stem cells. The extracellular matrix (ECM) was transformed into a custom hydrogel that served as a basis for printing.
This heart is composed of human cells and biological materials specific to the patient. In our process, these materials serve as biological links, sugar-based substances and proteins that can be used for 3D printing of complex tissue models … At this point, our heart in 3D is small, the size of the heart of 'a rabbit, but the big ones the same technology.
After being mixed with the hydrogel, the cells were efficiently differentiated into cardiac or endothelial cells to create patient-compatible, immune-compatible heart patches, with blood vessels and, subsequently, a heart complete corresponding to the immune, cellular, biochemical and anatomical synthesis of the patient. The difficulty of printing full organs was long overdue and we had already spoken about it in the past.
The development of this technology can completely solve the problem of compatibility and rejection of organs.
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