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Studies show that low levels of circulating vitamin K related to limitation of mobility in older people: study.
Washington: Scientists have found that a low level of circulating vitamin K is associated with reduced mobility and disability in the elderly. According to the study, this newly identified factor can be considered to maintain the mobility and independence of the elderly.
The study was published in the "Journal of Gerontology: Medical Sciences". "Because of the growth of our senior population, it is important for us to understand the diversity of risk factors for mobility disability," said Kyla Shea, first author and study correspondent. .
"A low vitamin K status has been associated with the onset of chronic diseases leading to disability, but the work to understand this link is in its infancy, and we are relying on previous studies that have shown that low levels of circulating vitamin K associated with slowing gait and increased risk of osteoarthritis, "she continued.
The new study examined two biomarkers: circulating vitamin K (phylloquinone) levels and a functional measure of vitamin K (plasma ucMGP). Using data from participants in the Health, Aging and Body Composition Study (Health ABC), the study found that older people with low levels of circulating vitamin K were more likely to develop a limitation of mobility and disability. The other biomarker, ucMGP plasma, has not shown clear association with the limitation of mobility and disability.
Specifically, older adults with low levels of circulating vitamin K were nearly 1.5 times more likely to develop mobility limitation and nearly twice as likely to develop motor impairment compared to those with sufficient levels. . This was true for both men and women.
"The relationship we have seen with low levels of circulating vitamin K further reinforces the association of vitamin K with a mobility disability," said Sarah Booth, lead author. "Although the two biomarkers we examined are known to reflect vitamin K status, additional factors, known or unknown, may also affect their level.Additional experiments are needed to understand the mechanisms of biomarkers and vitamin K and their role in mobility, "said Booth added.
The study used data from 635 men and 688 women aged 70 to 79 who participated in the ABC program of health. In Health ABC, mobility was assessed every six months for six to ten years through annual visits to the clinic and telephone interviews in the meantime.
Circulating vitamin K levels reflect the amount of vitamin K in the diet. The best dietary sources of vitamin K include leafy vegetables such as spinach, kale, broccoli and some dairy products. For an average adult, one cup of raw spinach provides 145 micrograms (μg) of vitamin K1, or 181% of daily value; a cup of raw cabbage provides 113 mcg or 141%, and half a cup of chopped cooked broccoli provides 110 mcg or 138%.
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