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According to a report by CBS Local (New York), researchers at Harvard University's Dana-Farber Cancer Institute have discovered that a cannabis flavonoid has "significant therapeutic potential" for the treatment of cancer. pancreas. In studies, the flavonoid derivative – FBL-03G – killed tumor cells in 70% of mice with pancreatic cancer.
Flavonoids, which are non-psychoactive, are naturally present in plants, vegetables and fruits, giving them, among other things, their colors. In cannabis, they represent only 0.14% of the plant.
Wilfred Ngwa, PhD, an assistant professor at Harvard and one of the researchers in the study, told Yahoo Lifestyle that the "most significant finding" of the study is "that a Targeted distribution on the flavonoid tumor, derived from cannabis, allowed both a local and metastatic tumor. cell destruction ". He added that this could "dramatically" increase survival rates for the disease.
In the study, the researchers note that the five-year survival rate of patients with pancreatic cancer is 8% and that it often metastasizes to other organs before diagnosis. According to the Pancreatic Cancer Action Network, it could be the second leading cause of cancer deaths in the United States next year.
"We were very surprised that the drug could inhibit the growth of cancer cells in other parts of the body, representing metastases, which were not targeted by treatment. This suggests that the immune system is also involved, and we are currently studying this mechanism. – Ngwa, CBS Local
Ngwa said the team hoped to complete the preclinical trials with the compound by the end of 2020.
The study was published in Frontiers in Oncology.
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