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Increasing coffee consumption may protect your liver and help prevent liver-related deaths, according to a recent report published in Food Pharmacology and Therapeutics. A group of Australian researchers looked at data from previous studies on coffee and liver disease and found that drinking more than two cups of coffee per day may help protect against death from liver disease.
“Increasing per capita coffee consumption to> 2 cups per day at the population level has the potential to prevent hundreds of thousands of liver-related deaths each year if the impact of coffee on death-related mortality is liver is confirmed in clinical trials, ”wrote Sarah Gardner of the liver transplant unit at Austin Hospital in Australia in the study.
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Gardner and his colleagues referred to the results of a previous study which said, “Compared to non-coffee drinkers, those who drank 2-3 cups per day had a 38% reduction in HCC. [hepatocellular carcinoma] risk and a 46% reduction in the risk of death from chronic liver disease (CLD). If people drank four or more cups a day, the reduction in risk of HCC was 41% and death from CLD was 71%. Other cohort studies have reported reductions in risk of a similar magnitude. “
The Australian team of researchers decided to estimate the potential impact that increased coffee consumption would have on overall liver-related mortality. They looked at the effect of consuming more than two cups and more than four cups / day per capita on liver-related deaths. The researchers used the Global Burden of Disease 2016 dataset for 194 countries to model the impact using risk ratios from a published study.
Increasing coffee consumption may protect your liver and help prevent liver-related deaths, according to a recent report. (iStock)
Gardner and colleagues found that if all countries had increased their per capita coffee consumption from less than two to more than two cups of coffee per day, the predicted number of liver-related deaths would have been 630,947 in 2016, with 452,861 deaths avoided. If the per capita coffee consumed were more than four cups per day, the predicted number of liver-related deaths in 2016 would have been 360,523, with 723,287 deaths averted, according to the study. Globally, the total number of liver-related deaths in 2016 was estimated at 1,240,201, according to the authors.
“Coffee clearly helps your liver,” Dr. Douglas Dieterich, hepatologist in the Mount Sinai Division of Liver Medicine and Gastroenterology, told Fox News. “This study demonstrates the larger-scale impact of previous studies[ that demonstrated benefits of coffee]. “
Dieterich also said he recommends the coffee to some of his patients, noting that it can help with certain liver diseases.
“Coffee is also good for primary biliary cholangitis (PBC),” an autoimmune liver disease that affects the bile ducts and could lead to cirrhosis, he said.
“The mechanism by which coffee provides protection against liver disease has not been clearly demonstrated, but it appears that caffeine is not the protective chemical. Of the many compounds in coffee, diterpenes and chlorogenic acids are the most studied in liver disease, ”the study authors said.
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“High coffee consumption has been correlated with better insulin sensitivity, suggesting that coffee may exert protective effects by alleviating insulin-induced liver fibrosis and / or NAFLD as a cofactor of progression of liver disease, ”they added.
Based on their data, the researchers said that coffee is an easily accessible and relatively safe health intervention that can reduce liver-related mortality worldwide. That said, the Australian research team said more research is needed to confirm coffee’s benefits on liver-related mortality.
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