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- Pfizer says the production of coronavirus vaccines will be dramatically improved as the company increases its manufacturing efficiency.
- The company has reduced the time it takes to manufacture a batch of COVID-19 vaccines to 60 days from the initial average of 110 days.
- Pfizer has also increased production at its three US factories involved in the vaccine manufacturing process.
Bloomberg Develop a coronavirus vaccine tracker that calculates how long it will take a specific country or state to achieve herd immunity – or immunize 75% of the population. On Saturday morning, the world needed almost 7 years to immunize 75% of the population with two-dose vaccines. That’s at a rate of over 4.6 million shots per day. The main problem with COVID-19 vaccination campaigns is that there simply aren’t enough doses for everyone, so most people who aren’t eligible for early vaccination will have to wait. several months to get their turn. But the number of vaccine candidates available is growing, as more drugs have completed their Phase 3 trials in recent weeks.
As for candidate vaccines already authorized for emergency use, they are speeding up production. Now Pfizer has just confirmed that it is able to significantly increase production.
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The Pfizer and BioNTech partnership was the first to produce an effective and safe vaccine candidate. Their mRNA drug was cleared for emergency use in mid-December. The drug is already in use in the United States, Europe, Israel and other countries, but companies cannot meet the demand. The vaccine comes with a two-dose schedule and injections should be given at least three weeks apart.
In addition to determining the drug’s efficacy and safety during trials, Pfizer had to develop new production lines and procedures for a type of drug that had never been manufactured before. Scientists have figured out how to make the whole process more efficient, and they can now cut the production time for a batch of vaccine from 110 days to 60 days on average.
“We call it ‘Project Light Speed’, and for a reason,” said Chaz Calitri. USA today. Calitri is Pfizer’s vice president of operations for sterile injectables and heads the Kalamazoo, Michigan plant. “Just last month, we doubled production.”
The report explains that the Pfizer vaccine is manufactured in three factories. The process begins in Chesterfield, Missouri, moves to Andover, Massachusetts, and ends in Kalamazoo, Michigan. The production system is based on how the vaccine was developed in the laboratory. With a regular vaccine, engineers would spend years improving efficiency and cost-effectiveness, but that can’t happen with a candidate vaccine during a pandemic.
“We went straight to commercial production,” Calitri said. But engineers continued to analyze the production process to improve efficiency. One of the things the engineers improved upon was the creation of the DNA material that starts the vaccination process. They initially needed 16 days for the process, but that time is now reduced to 9 or 10 days. Engineers said USA today that FDA regulations and best manufacturing practices are still being followed despite accelerated timelines for quality control and testing.
Pfizer has also increased production at the three factories and expects further improvements in the coming months. “We just demonstrated to ourselves that we can go from a phone call in March to now having delivered 50 to 60 million doses,” Calitri said.
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Chris Smith started writing about gadgets as a hobby, and before he even knew it he was sharing his take on tech with readers around the world. Whenever he doesn’t write about gadgets, he miserably fails to walk away from them, although he desperately tries. But that’s not necessarily a bad thing.
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