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Immunotherapy for Egg Allergy May Soon Allow Patients to Eat Eggs Safely | & nbspPhoto: & nbspGetty Images
Washington DC: A new study, presented by study author, Edwin Kim, at the annual conference of the American Academy of Allergy, Asthma and Immunology (AAAI) in San Francisco, revealed that after following up to four years of treatment with oral egg immunotherapy, able to incorporate eggs safely into their diet for five years.
In this regard, Kim said, "Egg allergy is one of the most common food allergies and usually occurs in early childhood. It carries a significant risk of severe allergic reactions and negatively affects the quality of life of allergic children. "
"Allergy seems to disappear with age, but it can last until the second decade of life. Any treatment that allows the introduction of eggs into the diet of an egg-allergic person provides nutritional benefits and peace of mind to the patient and family, "added Kim.
The trial started with eOIT or placebo in 55 patients with egg allergies aged 5 to 11 years. The treatments were randomized – 40 participants received eOIT and 15 received placebo.
The treatments lasted four years, during which patients were tested for egg sensitivity. Those who were considered insensitive – requiring a larger amount of egg to cause an allergic reaction – could consume 10 grams, or about two teaspoons, of pure egg without reaction.
The desensitized patients then stopped eOIT and were subjected to a new sensitivity test. Those who did not have a reaction were considered as no sustained reaction (SU). After finishing eOIT, it was recommended to add concentrated egg (scrambled egg, dish or shell) and / or oven (eggs incorporated in a cake) to the product. Five years after the allergy treatment, patients were asked to indicate how much egg they had eaten, how they had eaten it, how often they had eaten it. Had eaten and how they felt afterwards.
At the end of the OIT, 50% of patients were classified as SU, 28% of patients desensitized (without SU) and 22% non-desensitized. Of the patients classified as SU, 100% were able to eat baked eggs and concentrated eggs.
The study showed that the desensitized, non-desensitized, and placebo groups more variably ingested cooked and concentrated eggs and were more likely to exhibit symptoms related to ingestion.
Speaking of which, Kim said, "These results reinforce the effectiveness of eOIT as a sure way to desensitize children and young people allergic to eggs," adding, "Previous research also suggests that consumption of Eggs may reduce the time spent on allergy, so any amount of egg incorporated into the diet of an allergic patient is helpful. "
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