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04 October 2021
3 minutes to read
Source / Disclosures
Disclosures: Neither Blachman-Braun nor Mouzannar provides relevant financial information. Healio Primary Care was unable to determine the relevant financial information of Loeb and the other authors at the time of publication.
Men who ate healthy plant-based diets reduced their risk of prostate cancer and erectile dysfunction, according to data from three abstracts that were presented at the American Urological Association virtual meeting.
“That’s a lot of good news” Stacy Loeb, MD, a professor of urology and population health at New York University, said at a pre-recorded press conference. “There are certain dietary modifications that people can [make] with real potential benefits.
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The summaries included participants who followed an overall plant-based diet, which prioritizes the consumption of plant-based foods, and other participants who followed a healthy plant-based diet, which primarily emphasizes fruits, vegetables, whole grains, nuts and legumes rather than refined. cereals and plant foods high in sugar.
“Truly spectacular” results
In the first study, Loeb and his colleagues analyzed mortality data and food frequency questionnaires from 47,243 men who participated in the healthcare professional follow-up study. Participants were followed for up to 28 years. Of these, 6,660 were diagnosed with prostate cancer. Of these patients, 516 were at an advanced stage of the disease at the time of diagnosis, 958 were at a terminal stage and 807 had died.
Researchers reported that men younger than 65 at diagnosis who consumed more plant-based foods had a lower risk of advanced prostate cancer (HR = 0.68; 95% CI: 0.42-1.1). In younger men, greater consumption of a healthy plant-based diet was associated with a lower risk for all types of prostate cancer studied (HR = 0.81; 95% CI: 0, 7-0.95) and a terminal form of the disease (HR = 0.53; 95% CI: 0.32-0.9).
Stacy loeb
“Particularly in younger men, we found really dramatic and statistically lower risks of advanced prostate cancer, fatal prostate cancer, and fatal prostate cancer with greater consumption of healthy foods at herbal after controlling physical activity, [prostate-specific antigen] screening and many other potentially confounding variables, ”Loeb said.
Additional benefits related to the prostate
The second study looked at the levels of prostate-specific antigens in 1,399 men with a median age of 54 years who participated in the National Survey of Health and Nutrition.
Ali Mouzannar, BM, BCh, a study co-author and urology resident at Jackson Memorial Hospital in Miami, told the press conference that men who ate healthier plant-based foods were less likely to have an elevated PSA (OR = 0.47; 95% CI: 0.24-0.95).
“Clinicians can incorporate these findings into a shared decision-making process to promote healthier lifestyle choices. [and] reduce the likelihood of prostate biopsy and any morbidity associated with treatment, ”he said.
“Encouraging” results concerning erectile dysfunction
In the final study, Ruben Blachman-Braun, MD, MSc, a resident of the urology department at the University of Miami Hospital and colleagues analyzed data from the National Health and Nutrition Survey of 2,549 men aged 21 to 69 with frequencies of variable erections.
Researchers have reported that for every unit of increase in consumption of a healthy plant-based diet, its risk of decreased erectile dysfunction (OR = 0.98; 95% CI: 0.96-0.99).
“Our results are encouraging,” Blachman-Braun said at the press conference. “We are in line with our previous study in which we analyzed the association between testosterone and herbal diet.”
The references
Blachman-Braun, R et al. PD20-5. Plant-based diets are associated with a decreased risk of erectile dysfunction. Presented at: American Urological Association meeting; September 12, 2021 (virtual meeting).
Kim H, et al. PLOS Med. 2020; doi: 10.1371 / journal.pmed.1003371.
Loeb S, et al. MP32-06: Association of Plant-Based Diets with Prostate Cancer Risk. Presented at: American Urological Association meeting; September 12, 2021 (virtual meeting).
Mouzannar A, and l. Impact of plant-based diet on PSA level: data from the National Health and Nutrition Survey. Presented at: American Urological Association meeting; September 12, 2021 (virtual meeting).
Satija A, et al. J Am Coll Cardiol. 2017; doi: 10.1016 / j.jacc.2017.05.047.
Perspective
Stephen J. Freedland, MD
It has been known for some time that obesity can increase the risk of erectile dysfunction and prostate cancer. Based on this information, it was thought that factors related to lifestyle and in particular diet could be involved. However, the exact regimen for reducing these conditions is unknown. Some studies have shown that the Mediterranean diet can help reduce the risk of prostate cancer. Now, these summaries from the American Urological Association annual meeting suggest that a healthy plant-based diet may also help reduce, but not eliminate, the risk of this disease.
Whenever we talk about healthy plant-based nutrition with our patients, we need to emphasize what healthy eating means. I have had patients who avoid eating meat and tell me that they are doing themselves a great service in reducing their risk of contracting these diseases. However, some of them don’t realize that a healthy plant-based diet also means eliminating most simple sugars and all processed foods.
Therefore, make sure your patients understand the true meaning of a healthy plant-based diet, which is at its core “healthy”. Otherwise, there is probably little benefit to a plant-based diet unless they follow a healthy plant-based diet.
Stephen J. Freedland, MD
Warschaw Robertson Law Families Chair in Prostate Cancer
Director, Center for Integrated Cancer and Lifestyle Research
Associate Director, Cedars-Sinai Cancer
Cedars-Sinai Medical Center, Los Angeles
Disclosures: Freedland does not report any relevant financial information.
American Urological Association
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